Happy facial expression processing with different social interaction cues: An fMRI study of individuals with schizotypal personality traits

Jia Huang; Yi Wang; Zhen Jin; Xin Di; Tao Yang; Ruben C. Gur; Raquel E. Gur; David H.K. Shum; Eric F.C. Cheung; Raymond C.K. Chan

doi:10.1016/j.pnpbp.2013.02.004

Happy facial expression processing with different social interaction cues: An fMRI study of individuals with schizotypal personality traits

Jia Huang, Yi Wang, Zhen Jin, Xin Di, Tao Yang, Ruben C. Gur, Raquel E. Gur, David H.K. Shum, Eric F.C. Cheung, Raymond C.K. Chan

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

In daily life facial expressions change rapidly and the direction of change provides important clues about social interaction. The aim of conducting this study was to elucidate the dynamic happy facial expression processing with different social interaction cues in individuals with (n. =. 14) and without (n. =. 14) schizotypal personality disorder (SPD) traits. Using functional magnetic resonance imaging (fMRI), dynamic happy facial expression processing was examined by presenting video clips depicting happiness appearing and disappearing under happiness inducing ('praise') or reducing ('blame') interaction cues. The happiness appearing condition consistently elicited more brain activations than the happiness disappearing condition in the posterior cingulate bilaterally in all participants. Further analyses showed that the SPD group was less deactivated than the non-SPD group in the right anterior cingulate cortex in the happiness appearing-disappearing contrast. The SPD group deactivated more than the non-SPD group in the left posterior cingulate and right superior temporal gyrus in the praise-blame contrast. Moreover, the incongruence of cues and facial expression activated the frontal-thalamus-caudate-parietal network, which is involved in emotion recognition and conflict resolution. These results shed light on the neural basis of social interaction deficits in individuals with schizotypal personality traits.

Original language	English (US)
Pages (from-to)	108-117
Number of pages	10
Journal	Progress in Neuro-Psychopharmacology and Biological Psychiatry
Volume	44
DOIs	https://doi.org/10.1016/j.pnpbp.2013.02.004
State	Published - Jul 1 2013
Externally published	Yes

All Science Journal Classification (ASJC) codes

Pharmacology
Biological Psychiatry

Keywords

Functional imaging
Happy facial expression
Schizotypal personality traits
Social interaction cues

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10.1016/j.pnpbp.2013.02.004

Cite this

Huang, J., Wang, Y., Jin, Z., Di, X., Yang, T., Gur, R. C., Gur, R. E., Shum, D. H. K., Cheung, E. F. C., & Chan, R. C. K. (2013). Happy facial expression processing with different social interaction cues: An fMRI study of individuals with schizotypal personality traits. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 44, 108-117. https://doi.org/10.1016/j.pnpbp.2013.02.004

@article{73e285333a63416fba1ce168b2846799,

title = "Happy facial expression processing with different social interaction cues: An fMRI study of individuals with schizotypal personality traits",

abstract = "In daily life facial expressions change rapidly and the direction of change provides important clues about social interaction. The aim of conducting this study was to elucidate the dynamic happy facial expression processing with different social interaction cues in individuals with (n. =. 14) and without (n. =. 14) schizotypal personality disorder (SPD) traits. Using functional magnetic resonance imaging (fMRI), dynamic happy facial expression processing was examined by presenting video clips depicting happiness appearing and disappearing under happiness inducing ('praise') or reducing ('blame') interaction cues. The happiness appearing condition consistently elicited more brain activations than the happiness disappearing condition in the posterior cingulate bilaterally in all participants. Further analyses showed that the SPD group was less deactivated than the non-SPD group in the right anterior cingulate cortex in the happiness appearing-disappearing contrast. The SPD group deactivated more than the non-SPD group in the left posterior cingulate and right superior temporal gyrus in the praise-blame contrast. Moreover, the incongruence of cues and facial expression activated the frontal-thalamus-caudate-parietal network, which is involved in emotion recognition and conflict resolution. These results shed light on the neural basis of social interaction deficits in individuals with schizotypal personality traits.",

keywords = "Functional imaging, Happy facial expression, Schizotypal personality traits, Social interaction cues",

author = "Jia Huang and Yi Wang and Zhen Jin and Xin Di and Tao Yang and Gur, {Ruben C.} and Gur, {Raquel E.} and Shum, {David H.K.} and Cheung, {Eric F.C.} and Chan, {Raymond C.K.}",

note = "Funding Information: This work was supported by a grant from the Strategic Priority Research Programme (B) of the Chinese Academy of Sciences ( XDB02030200 ) and the National Key Technologies R&D Programme ( 2012BAI36B01 ), the National Science Fund China ( 81088001 , 91132701 ), and a grant from the Knowledge Innovation Project of the Chinese Academy of Sciences ( KSCX2-EW-J-8 ), to Raymond Chan. Dr. Jia Huang acknowledges supports from the National Science Fund China ( 31100747 ), the Young Investigator Scientific Fund of the Institute of Psychology , Chinese Academy of Sciences ( YOCX031S01 ) and funding from the Key Laboratory of Mental Health, Institute of Psychology , Chinese Academy of Sciences. The study was also supported by the initiation fund of the CAS/SAFEA International Partnership Programme for Creative Research Teams to Raymond Chan, Ruben Gur, and David Shum ( Y2CX131003 ). These funding agents had no further role in the study design; in the collection, analysis and interpretation of the data; in the writing of the manuscript; and in the decision to submit the paper for publication.",

year = "2013",

month = jul,

day = "1",

doi = "10.1016/j.pnpbp.2013.02.004",

language = "English (US)",

volume = "44",

pages = "108--117",

journal = "Progress in Neuro-Psychopharmacology and Biological Psychiatry",

issn = "0278-5846",

publisher = "Elsevier Inc.",

}

Huang, J, Wang, Y, Jin, Z, Di, X, Yang, T, Gur, RC, Gur, RE, Shum, DHK, Cheung, EFC & Chan, RCK 2013, 'Happy facial expression processing with different social interaction cues: An fMRI study of individuals with schizotypal personality traits', Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 44, pp. 108-117. https://doi.org/10.1016/j.pnpbp.2013.02.004

TY - JOUR

T1 - Happy facial expression processing with different social interaction cues

T2 - An fMRI study of individuals with schizotypal personality traits

AU - Huang, Jia

AU - Wang, Yi

AU - Jin, Zhen

AU - Di, Xin

AU - Yang, Tao

AU - Gur, Ruben C.

AU - Gur, Raquel E.

AU - Shum, David H.K.

AU - Cheung, Eric F.C.

AU - Chan, Raymond C.K.

N1 - Funding Information: This work was supported by a grant from the Strategic Priority Research Programme (B) of the Chinese Academy of Sciences ( XDB02030200 ) and the National Key Technologies R&D Programme ( 2012BAI36B01 ), the National Science Fund China ( 81088001 , 91132701 ), and a grant from the Knowledge Innovation Project of the Chinese Academy of Sciences ( KSCX2-EW-J-8 ), to Raymond Chan. Dr. Jia Huang acknowledges supports from the National Science Fund China ( 31100747 ), the Young Investigator Scientific Fund of the Institute of Psychology , Chinese Academy of Sciences ( YOCX031S01 ) and funding from the Key Laboratory of Mental Health, Institute of Psychology , Chinese Academy of Sciences. The study was also supported by the initiation fund of the CAS/SAFEA International Partnership Programme for Creative Research Teams to Raymond Chan, Ruben Gur, and David Shum ( Y2CX131003 ). These funding agents had no further role in the study design; in the collection, analysis and interpretation of the data; in the writing of the manuscript; and in the decision to submit the paper for publication.

PY - 2013/7/1

Y1 - 2013/7/1

N2 - In daily life facial expressions change rapidly and the direction of change provides important clues about social interaction. The aim of conducting this study was to elucidate the dynamic happy facial expression processing with different social interaction cues in individuals with (n. =. 14) and without (n. =. 14) schizotypal personality disorder (SPD) traits. Using functional magnetic resonance imaging (fMRI), dynamic happy facial expression processing was examined by presenting video clips depicting happiness appearing and disappearing under happiness inducing ('praise') or reducing ('blame') interaction cues. The happiness appearing condition consistently elicited more brain activations than the happiness disappearing condition in the posterior cingulate bilaterally in all participants. Further analyses showed that the SPD group was less deactivated than the non-SPD group in the right anterior cingulate cortex in the happiness appearing-disappearing contrast. The SPD group deactivated more than the non-SPD group in the left posterior cingulate and right superior temporal gyrus in the praise-blame contrast. Moreover, the incongruence of cues and facial expression activated the frontal-thalamus-caudate-parietal network, which is involved in emotion recognition and conflict resolution. These results shed light on the neural basis of social interaction deficits in individuals with schizotypal personality traits.

AB - In daily life facial expressions change rapidly and the direction of change provides important clues about social interaction. The aim of conducting this study was to elucidate the dynamic happy facial expression processing with different social interaction cues in individuals with (n. =. 14) and without (n. =. 14) schizotypal personality disorder (SPD) traits. Using functional magnetic resonance imaging (fMRI), dynamic happy facial expression processing was examined by presenting video clips depicting happiness appearing and disappearing under happiness inducing ('praise') or reducing ('blame') interaction cues. The happiness appearing condition consistently elicited more brain activations than the happiness disappearing condition in the posterior cingulate bilaterally in all participants. Further analyses showed that the SPD group was less deactivated than the non-SPD group in the right anterior cingulate cortex in the happiness appearing-disappearing contrast. The SPD group deactivated more than the non-SPD group in the left posterior cingulate and right superior temporal gyrus in the praise-blame contrast. Moreover, the incongruence of cues and facial expression activated the frontal-thalamus-caudate-parietal network, which is involved in emotion recognition and conflict resolution. These results shed light on the neural basis of social interaction deficits in individuals with schizotypal personality traits.

KW - Functional imaging

KW - Happy facial expression

KW - Schizotypal personality traits

KW - Social interaction cues

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JO - Progress in Neuro-Psychopharmacology and Biological Psychiatry

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ER -

Happy facial expression processing with different social interaction cues: An fMRI study of individuals with schizotypal personality traits

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