Highly efficient ionization of phosphopeptides at low pH by desorption electrospray ionization mass spectrometry

Ning Pan, Pengyuan Liu, Weidong Cui, Bo Tang, Jingmin Shi, Hao Chen

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

A fast and novel strategy for efficient ionization of phosphopeptides in mixtures is reported, in which the sample is acidified to low pH to suppress the deprotonation of phosphate groups and then followed by direct analysis using liquid sample desorption electrospray ionization mass spectrometry (DESI-MS).

Original languageEnglish (US)
Pages (from-to)1321-1324
Number of pages4
JournalAnalyst
Volume138
Issue number5
DOIs
StatePublished - Mar 7 2013
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Environmental Chemistry
  • Spectroscopy
  • Electrochemistry

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