TY - JOUR
T1 - Human spaceflight and space adaptations
T2 - Computational simulation of gravitational unloading on the spine
AU - Townsend, Molly T.
AU - Sarigul-Klijn, Nesrin
N1 - Funding Information:
This work was partially supported by the NSF under Grant No. 1148897 .
Funding Information:
This work was partially supported by the NSF under Grant No. 1148897.
Publisher Copyright:
© 2018 IAA
PY - 2018/4
Y1 - 2018/4
N2 - Living in reduced gravitational environments for a prolonged duration such, as a fly by mission to Mars or an extended stay at the international space station, affects the human body - in particular, the spine. As the spine adapts to spaceflight, morphological and physiological changes cause the mechanical integrity of the spinal column to be compromised, potentially endangering internal organs, nervous health, and human body mechanical function. Therefore, a high fidelity computational model and simulation of the whole human spine was created and validated for the purpose of investigating the mechanical integrity of the spine in crew members during exploratory space missions. A spaceflight exposed spine has been developed through the adaptation of a three-dimensional nonlinear finite element model with the updated Lagrangian formulation of a healthy ground-based human spine in vivo. Simulation of the porohyperelastic response of the intervertebral disc to mechanical unloading resulted in a model capable of accurately predicting spinal swelling/lengthening, spinal motion, and internal stress distribution. The curvature of this space adaptation exposed spine model was compared to a control terrestrial-based finite element model, indicating how the shape changed. Finally, the potential of injury sites to crew members are predicted for a typical 9 day mission.
AB - Living in reduced gravitational environments for a prolonged duration such, as a fly by mission to Mars or an extended stay at the international space station, affects the human body - in particular, the spine. As the spine adapts to spaceflight, morphological and physiological changes cause the mechanical integrity of the spinal column to be compromised, potentially endangering internal organs, nervous health, and human body mechanical function. Therefore, a high fidelity computational model and simulation of the whole human spine was created and validated for the purpose of investigating the mechanical integrity of the spine in crew members during exploratory space missions. A spaceflight exposed spine has been developed through the adaptation of a three-dimensional nonlinear finite element model with the updated Lagrangian formulation of a healthy ground-based human spine in vivo. Simulation of the porohyperelastic response of the intervertebral disc to mechanical unloading resulted in a model capable of accurately predicting spinal swelling/lengthening, spinal motion, and internal stress distribution. The curvature of this space adaptation exposed spine model was compared to a control terrestrial-based finite element model, indicating how the shape changed. Finally, the potential of injury sites to crew members are predicted for a typical 9 day mission.
KW - Finite element method
KW - Gravitational unloading
KW - Human spaceflight
KW - Long duration spaceflight
KW - Swelling
KW - Tissue damage
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U2 - 10.1016/j.actaastro.2018.01.015
DO - 10.1016/j.actaastro.2018.01.015
M3 - Article
AN - SCOPUS:85041413151
SN - 0094-5765
VL - 145
SP - 18
EP - 27
JO - Acta Astronautica
JF - Acta Astronautica
ER -