Imaging asynchronous mechanical activation of the paced heart with tagged MRI

Elliot R. McVeigh; Frits W. Prinzen; Bradley T. Wyman; Joshua E. Tsitlik; Henry R. Halperin; William C. Hunter

doi:10.1002/mrm.1910390402

Imaging asynchronous mechanical activation of the paced heart with tagged MRI

Elliot R. McVeigh, Frits W. Prinzen, Bradley T. Wyman, Joshua E. Tsitlik, Henry R. Halperin, William C. Hunter

Research output: Contribution to journal › Article › peer-review

67 Scopus citations

Abstract

A method for imaging the rapid temporal-spatial evolution of myocardial deformations in the paced heart is proposed. High time resolution-tagged MR images were obtained after stimulation of the myocardium with an MR- compatible pacing system. The Images were analyzed to reconstruct dynamic models of local 3D strains over the entire left ventricle during systole. Normal canine hearts were studied in vivo with pacing sites on the right atrium, left ventricular free wall and right ventricular apex. This method clearly resolved local variations in myocardial contraction patterns caused by ventricular pacing. Potential applications are noninvasive determination of electrical conduction abnormalities and the evaluation of new pacing therapies.

Original language	English (US)
Pages (from-to)	507-513
Number of pages	7
Journal	Magnetic Resonance in Medicine
Volume	39
Issue number	4
DOIs	https://doi.org/10.1002/mrm.1910390402
State	Published - Apr 1998
Externally published	Yes

All Science Journal Classification (ASJC) codes

Radiology Nuclear Medicine and imaging

Keywords

Heart
MRI
Pacing
Tagging

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10.1002/mrm.1910390402

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title = "Imaging asynchronous mechanical activation of the paced heart with tagged MRI",

abstract = "A method for imaging the rapid temporal-spatial evolution of myocardial deformations in the paced heart is proposed. High time resolution-tagged MR images were obtained after stimulation of the myocardium with an MR- compatible pacing system. The Images were analyzed to reconstruct dynamic models of local 3D strains over the entire left ventricle during systole. Normal canine hearts were studied in vivo with pacing sites on the right atrium, left ventricular free wall and right ventricular apex. This method clearly resolved local variations in myocardial contraction patterns caused by ventricular pacing. Potential applications are noninvasive determination of electrical conduction abnormalities and the evaluation of new pacing therapies.",

keywords = "Heart, MRI, Pacing, Tagging",

author = "McVeigh, {Elliot R.} and Prinzen, {Frits W.} and Wyman, {Bradley T.} and Tsitlik, {Joshua E.} and Halperin, {Henry R.} and Hunter, {William C.}",

year = "1998",

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AU - McVeigh, Elliot R.

AU - Prinzen, Frits W.

AU - Wyman, Bradley T.

AU - Tsitlik, Joshua E.

AU - Halperin, Henry R.

AU - Hunter, William C.

PY - 1998/4

Y1 - 1998/4

N2 - A method for imaging the rapid temporal-spatial evolution of myocardial deformations in the paced heart is proposed. High time resolution-tagged MR images were obtained after stimulation of the myocardium with an MR- compatible pacing system. The Images were analyzed to reconstruct dynamic models of local 3D strains over the entire left ventricle during systole. Normal canine hearts were studied in vivo with pacing sites on the right atrium, left ventricular free wall and right ventricular apex. This method clearly resolved local variations in myocardial contraction patterns caused by ventricular pacing. Potential applications are noninvasive determination of electrical conduction abnormalities and the evaluation of new pacing therapies.

AB - A method for imaging the rapid temporal-spatial evolution of myocardial deformations in the paced heart is proposed. High time resolution-tagged MR images were obtained after stimulation of the myocardium with an MR- compatible pacing system. The Images were analyzed to reconstruct dynamic models of local 3D strains over the entire left ventricle during systole. Normal canine hearts were studied in vivo with pacing sites on the right atrium, left ventricular free wall and right ventricular apex. This method clearly resolved local variations in myocardial contraction patterns caused by ventricular pacing. Potential applications are noninvasive determination of electrical conduction abnormalities and the evaluation of new pacing therapies.

KW - Heart

KW - MRI

KW - Pacing

KW - Tagging

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JO - Magnetic Resonance in Medicine

JF - Magnetic Resonance in Medicine

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Imaging asynchronous mechanical activation of the paced heart with tagged MRI

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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