Improved Hessian multiscale enhancement filter

Jinzhu Yang, Shuang Ma, Qi Sun, Wenjun Tan, Mengjia Xu, Nan Chen, Dazhe Zhao

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Traditional Hessian multiscale filter consider only the local geometric feature but not the global grayscale information. In medical image analysis, Hessian filter is usually used to enhance the blood vessels. However, it also produces some pseudo vascular structures or some isolate noise points, such as the nasal soft tissues that have the similar shape with the vessels in MRA data, which will increase the difficulty of cerebrovascular segmentation. To resolve this issue, an improved Hessian multiscale filter is proposed in this paper. An image grayscale factor is added to the vascular similarity function computed by Hessian matrix eigenvalue. This method is experimented on brain MRA data and lung CTA data. Experimental results show that this method can enhance vascular structures, and simultaneously reduce the appearance of the pseudo vascular structures and the isolated noise points.

Original languageEnglish (US)
Pages (from-to)3267-3275
Number of pages9
JournalBio-Medical Materials and Engineering
Issue number6
StatePublished - 2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biomaterials
  • Biomedical Engineering


  • CT image
  • Grayscale
  • Hessian filter
  • MRA image
  • Multiscale enhancement


Dive into the research topics of 'Improved Hessian multiscale enhancement filter'. Together they form a unique fingerprint.

Cite this