TY - JOUR
T1 - Introduction to focus issue
T2 - Rhythms and dynamic transitions in neurological disease: Modeling, computation, and experiment
AU - Kaper, Tasso J.
AU - Kramer, Mark A.
AU - Rotstein, Horacio G.
N1 - Funding Information:
This work was partially supported by NINDS R01NS072023 (MAK), NSF DMS-0817241 (HGR), NSF DMS-1313861 (HGR), and NSF DMS-1109587 (TJK). M.A.K. holds a Career Award at the Scientific Interface from the Burroughs Wellcome Fund.
PY - 2013/10/2
Y1 - 2013/10/2
N2 - Rhythmic neuronal oscillations across a broad range of frequencies, as well as spatiotemporal phenomena, such as waves and bumps, have been observed in various areas of the brain and proposed as critical to brain function. While there is a long and distinguished history of studying rhythms in nerve cells and neuronal networks in healthy organisms, the association and analysis of rhythms to diseases are more recent developments. Indeed, it is now thought that certain aspects of diseases of the nervous system, such as epilepsy, schizophrenia, Parkinson's, and sleep disorders, are associated with transitions or disruptions of neurological rhythms. This focus issue brings together articles presenting modeling, computational, analytical, and experimental perspectives about rhythms and dynamic transitions between them that are associated to various diseases.
AB - Rhythmic neuronal oscillations across a broad range of frequencies, as well as spatiotemporal phenomena, such as waves and bumps, have been observed in various areas of the brain and proposed as critical to brain function. While there is a long and distinguished history of studying rhythms in nerve cells and neuronal networks in healthy organisms, the association and analysis of rhythms to diseases are more recent developments. Indeed, it is now thought that certain aspects of diseases of the nervous system, such as epilepsy, schizophrenia, Parkinson's, and sleep disorders, are associated with transitions or disruptions of neurological rhythms. This focus issue brings together articles presenting modeling, computational, analytical, and experimental perspectives about rhythms and dynamic transitions between them that are associated to various diseases.
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U2 - 10.1063/1.4856276
DO - 10.1063/1.4856276
M3 - Article
C2 - 24387579
AN - SCOPUS:84891454658
SN - 1054-1500
VL - 23
JO - Chaos
JF - Chaos
IS - 4
M1 - 046001
ER -