Introduction to mitochondria biology

Christian Thomasa, Sara C. Zapico

Research output: Chapter in Book/Report/Conference proceedingChapter


Mitochondria are intracellular organelles that evolved from an ancient endosymbiotic a-purple bacteria ingested by an eukaryotic ancestor approximately 1.5 billion years ago (Gray 2001). As a consequence of their origin, mitochondria have a doublemembrane structure, composed by an outer membrane, highly permeable with many pores surrounding the inter-membrane space and an impermeable inner membrane, delimiting the internal matrix (Frey and Mannella 2000) (Fig. 1).

Original languageEnglish (US)
Title of host publicationMechanisms Linking Aging, Diseases and Biological Age Estimation
PublisherCRC Press
Number of pages8
ISBN (Electronic)9781498709705
ISBN (Print)9781498709699
StatePublished - Jan 1 2017
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Social Sciences
  • General Medicine
  • General Biochemistry, Genetics and Molecular Biology


  • ATP
  • Bacteria
  • D-loop
  • Energy
  • Heteroplasmy
  • Homoplasmy
  • Hypervariable region 1
  • Hypervariable region 2
  • Maternal inheritage
  • Mitochondria
  • MtDNA
  • Oxidative phosphorylation
  • Reactive oxygen species


Dive into the research topics of 'Introduction to mitochondria biology'. Together they form a unique fingerprint.

Cite this