Abstract
Mitochondria are intracellular organelles that evolved from an ancient endosymbiotic a-purple bacteria ingested by an eukaryotic ancestor approximately 1.5 billion years ago (Gray 2001). As a consequence of their origin, mitochondria have a doublemembrane structure, composed by an outer membrane, highly permeable with many pores surrounding the inter-membrane space and an impermeable inner membrane, delimiting the internal matrix (Frey and Mannella 2000) (Fig. 1).
| Original language | English (US) |
|---|---|
| Title of host publication | Mechanisms Linking Aging, Diseases and Biological Age Estimation |
| Publisher | CRC Press |
| Pages | 185-192 |
| Number of pages | 8 |
| ISBN (Electronic) | 9781498709705 |
| ISBN (Print) | 9781498709699 |
| DOIs | |
| State | Published - Jan 1 2017 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- General Social Sciences
- General Medicine
- General Biochemistry, Genetics and Molecular Biology
Keywords
- ATP
- Bacteria
- D-loop
- Energy
- Heteroplasmy
- Homoplasmy
- Hypervariable region 1
- Hypervariable region 2
- Maternal inheritage
- Mitochondria
- MtDNA
- Oxidative phosphorylation
- Reactive oxygen species