Investigation of the donor and acceptor range for chiral carboligation catalyzed by the E1 component of the 2-oxoglutarate dehydrogenase complex

Keyphrases

• High Enantiomeric Excess 100%
• Carboligation 100%
• 2-Oxoglutarate Dehydrogenase Complex 100%
• 2-oxoglutarate Dehydrogenase 50%
• Escherichia Coli 50%
• Enzyme Complex 50%
• 2-oxoacids 50%
• Natural Substrate 50%
• Good Yield 50%
• 2-oxoglutarate 50%
• Methylglyoxal 50%
• Chiral Molecules 50%
• Ethyl Glyoxylate 50%
• Thiamine Diphosphate-dependent Enzymes 50%
• Multiple Functional Groups 50%
• Acceptor Substrate 50%
• Bond-forming 50%
• Donor Substrate 50%
• Glyoxylate 50%
• Chiral Synthesis 50%
• Carboligase 50%

Chemistry

• Donor 100%
• Enantiomer 100%
• Methylglyoxal 50%
• Glyoxylate 50%
• Thiamine 50%
• Ethyl Glyoxylate 50%