Kinetic Analysis of Hydroxide-Catalyzed, Aerobic Oxidation of 2-Mercaptoethanol

Nellone Reid, Robert Barat

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Experiments and mechanistic kinetic analyses are conducted for the hydroxide-catalyzed, aerobic oxidation of the thiol 2-mercaptoethanol (2-ME) to water and the corresponding disulfide at 22°C and 1 atm total pressure in tetrahydrofuran. The experiments are performed in an isothermal, bench-scale reactor with a maintained O2 partial pressure. The 2-ME concentrations are measured using gas chromatograph/flame ionization detector (GC/FID). The mixture includes a small amount of aqueous NaOH required to activate the thiol (RSH) to thiolate (RS). The observed 2-ME conversion is first order in 2-ME concentration. A multistep mechanism is proposed consistent with the observed kinetics. The rate-determining step is the coupling of RS to dissolved O2, with an estimated rate constant k = 1.93 × 10−6 liter/mmol h.

Original languageEnglish (US)
Pages (from-to)1231-1234
Number of pages4
JournalChemical Engineering Communications
Volume202
Issue number9
DOIs
StatePublished - Sep 2 2015

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

Keywords

  • 2-Mercaptoethanol
  • Catalysis
  • Kinetics
  • Mechanism
  • Oxidation
  • Sodium hydroxide

Fingerprint Dive into the research topics of 'Kinetic Analysis of Hydroxide-Catalyzed, Aerobic Oxidation of 2-Mercaptoethanol'. Together they form a unique fingerprint.

Cite this