Abstract
Lanthanide-doped upconversion nanoparticles (UCNPs) possess unique anti-Stokes optical properties, in which low-energy near-infrared (NIR) excitation can be converted into high-energy UV and/or visible emission with pronounced luminescence and chemical stability. Due to the rapid development of synthesis chemistry, lanthanide-doped UCNPs can be fabricated with narrow distribution and modulated physical behaviors. These unique characters endow them unique NIR-driven imaging/delivery/therapeutic applications, especially in the cases of the deep tissue environments. Herein, we introduce both the basic concepts and the up-to-date progresses of UCNPs in material engineering, toxicology, and bio-applications in imaging, molecular delivery, and tumor therapeutics.
Original language | English (US) |
---|---|
Pages (from-to) | 139-164 |
Number of pages | 26 |
Journal | Springer Series in Biomaterials Science and Engineering |
Volume | 6 |
DOIs | |
State | Published - 2016 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Biomedical Engineering
- Biomaterials
Keywords
- Drug delivery
- Optical imaging
- Optical therapy
- Upconversion nanoparticles