Lattice Boltzmann methods for bioengineering applications

D. V. Papavassiliou, N. H. Pham, O. E. Kadri, R. S. Voronov

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Abstract

Computational techniques have gained wider acceptance and application within biomedical and bioengineering applications. Among the most potent numerical techniques for simulating biological flows in complex geometries is the lattice Boltzmann method (LBM). It is appropriate for cases where the implementation of boundary conditions can be difficult when applying other methods and in cases where parallelization of the computations is needed to simulate large systems. In this work, we report on the LBM methodology and applications, drawing mainly from our research on using LBM to simulate flows in scaffolds and perfusion bioreactors. The flow-induced stresses can be predicted with LBM, and vital information about the successful culture of cells can be generated. In addition to the simulation of flow, the LBM can be used in conjunction with particle-based techniques to simulate mass transfer in the flow field. The combination of LBM with Lagrangian particle tracking or Lagrangian scalar tracking is also highlighted.

Original languageEnglish (US)
Title of host publicationNumerical Methods and Advanced Simulation in Biomechanics and Biological Processes
PublisherElsevier Inc.
Pages415-429
Number of pages15
ISBN (Electronic)9780128117194
ISBN (Print)9780128117187
DOIs
StatePublished - Jan 1 2018

All Science Journal Classification (ASJC) codes

  • Engineering(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Keywords

  • Bone tissue engineering
  • Lattice Boltzmann
  • Scaffold design
  • Thrombosis

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