Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications

Burcin Izbudak, Berivan Cecen, Ingrid Anaya, Amir K. Miri, Ayca Bal-Ozturk, Erdal Karaoz

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations


Layered double hydroxides (LDHs), when incorporated into biomaterials, provide a tunable composition, controllable particle size, anion exchange capacity, pH-sensitive solubility, high-drug loading efficiency, efficient gene and drug delivery, controlled release and effective intracellular uptake, natural biodegradability in an acidic medium, and negligible toxicity. In this review, we study potential applications of LDH-based nanocomposite scaffolds for tissue engineering. We address how LDHs provide new solutions for nanostructure stability and enhancein vivostudies' success.

Original languageEnglish (US)
Pages (from-to)30237-30252
Number of pages16
JournalRSC Advances
Issue number48
StatePublished - Sep 9 2021
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • General Chemical Engineering


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