Lipid droplets are intracellular mechanical stressors that impair hepatocyte function

Keyphrases

• Cancer Development 20%
• Cell Response 20%
• Cellular Components 20%
• Chromatin Condensation 20%
• Cirrhosis 20%
• Disease Development 20%
• External Mechanical Stress 20%
• External Stress 20%
• Hepatocellular Carcinoma 20%
• Hepatocyte Function 100%
• Hepatocytes 20%
• Internal Stress 20%
• Lipid Droplets 100%
• Liver 20%
• Liver Lipid 20%
• Major Risk Factors 20%
• Mathematical Modeling 20%
• Matrix Stiffening 20%
• Mechanical Interaction 20%
• Mechanical Stress 20%
• Membrane Tension 20%
• Monounsaturated Fatty Acids 20%
• Multiple Tissues 20%
• Non-alcoholic Fatty Liver Disease (NAFLD) 20%
• Non-cirrhotic 20%
• Nuclear Deformation 20%
• Nuclear Membrane 20%
• Oleate 20%
• Primary Hepatocytes 20%
• Soft Tissue 20%
• Stiffness 20%
• Tissue Stiffening 20%

Biochemistry, Genetics and Molecular Biology

• Chromatin Condensation 20%
• Hepatocyte 40%
• Lipid Droplet 100%
• Liver Function 100%
• Mechanical Stress 40%
• Monounsaturated Fat 20%
• Nuclear Membrane 20%
• Rigidity 20%
• Tension 20%