Localization of the site of effect of a wasp's venom in the cockroach escape circuitry

Frederic Libersat, G. Haspel, J. Casagrand, K. Fouad

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

The parasitic wasp Ampulex compressa stings a cockroach Periplaneta americana in the neck, toward the head ganglia (the brain and subesophageal ganglion). In the present study, our aim was to identify the head ganglion that is the target of the venom and the mechanisms by which the venom blocks the thoracic portion of the escape neuronal circuitry. Because the escape responses elicited by a wind stimulus in brainless and sham-operated animals were similar, we propose that the venom effect is on the subesophageal ganglion. Apparently, the subesophageal ganglion modulates the thoracic portion of the escape circuit. Recordings of thoracic interneuron responses to the input from the abdominal giant interneurons showed that the thoracic interneurons receive synaptic drive from these interneurons in control and in stung animals. Unlike normal cockroaches, which use both fast and slow motoneurons for producing rapid escape movements, stung animals activate only the slow motoneuron. However, we show that in stung animals, the fast motoneuron still can be recruited with bath application of pilocarpine, a muscarinic agonist. These results indicate that the descending control from the subesophageal ganglion is presumably exerted on the premotor thoracic interneurons to motoneurons connection of the thoracic escape circuitry.

Original languageEnglish (US)
Pages (from-to)333-345
Number of pages13
JournalJournal of Comparative Physiology - A Sensory, Neural, and Behavioral Physiology
Volume184
Issue number3
DOIs
StatePublished - Mar 1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Physiology
  • Animal Science and Zoology
  • Behavioral Neuroscience

Keywords

  • Insects
  • Subesophageal ganglion
  • Thoracic interneurons Wasp
  • Venom

Fingerprint Dive into the research topics of 'Localization of the site of effect of a wasp's venom in the cockroach escape circuitry'. Together they form a unique fingerprint.

Cite this