TY - JOUR
T1 - Longitudinal assessment of neuropsychological functioning, psychiatric status, functional disability and employment status in chronic fatigue syndrome
AU - Tiersky, Lana A.
AU - DeLuca, John
AU - Hill, Nancy
AU - Dhar, Sunil K.
AU - Johnson, Susan K.
AU - Lange, Gudrun
AU - Rappolt, Gabrielle
AU - Natelson, Benjamin H.
N1 - Funding Information:
This research was supported by Grants U0I–AI32247 and R01–MH52810 from the National Institutes of Health. Requests for reprints should be sent to Lana A. Tiersky, School of Psychology, Fairleigh Dickinson University, 1000 River Road, Mail Stop T-WH1-01, Teaneck, NJ 07666, USA.
PY - 2001
Y1 - 2001
N2 - The longitudinal course of subjective and objective neuropsychological functioning, psychological functioning, disability level, and employment status in chronic fatigue syndrome (CFS) was examined. The relations among several key outcomes at follow-up, as well as the baseline characteristics that predict change (e.g., improvement), were also evaluated. The study sample consisted of 35 individuals who met the 1988 and 1994 CFS case definition criteria of the Centers for Disease Control (CDC) at intake. Participants were evaluated a mean of 41.9 (SEM = 1.7) months following their initial visit (range = 24-63 months). Results indicated that objective and subjective attention abilities, mood, level of fatigue, and disability improve over time in individuals with CFS. Moreover, improvements in these areas were found to be interrelated at follow-up. Finally, psychiatric status, age, and between-test duration were significant predictors of outcome. Overall, the prognosis for CFS appears to be poor, as the majority of participants remained functionally impaired over time and were unemployed at follow-up, despite the noted improvements.
AB - The longitudinal course of subjective and objective neuropsychological functioning, psychological functioning, disability level, and employment status in chronic fatigue syndrome (CFS) was examined. The relations among several key outcomes at follow-up, as well as the baseline characteristics that predict change (e.g., improvement), were also evaluated. The study sample consisted of 35 individuals who met the 1988 and 1994 CFS case definition criteria of the Centers for Disease Control (CDC) at intake. Participants were evaluated a mean of 41.9 (SEM = 1.7) months following their initial visit (range = 24-63 months). Results indicated that objective and subjective attention abilities, mood, level of fatigue, and disability improve over time in individuals with CFS. Moreover, improvements in these areas were found to be interrelated at follow-up. Finally, psychiatric status, age, and between-test duration were significant predictors of outcome. Overall, the prognosis for CFS appears to be poor, as the majority of participants remained functionally impaired over time and were unemployed at follow-up, despite the noted improvements.
KW - Chronic fatigue
KW - Follow-up
KW - Neuropsychological assessment
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U2 - 10.1207/S15324826AN0801_6
DO - 10.1207/S15324826AN0801_6
M3 - Article
C2 - 11388123
AN - SCOPUS:0035006641
SN - 0908-4282
VL - 8
SP - 41
EP - 50
JO - Applied Neuropsychology
JF - Applied Neuropsychology
IS - 1
ER -