Modulated optically computed phase microscopy for high-resolution, high-sensitivity label-free imaging

Xuan Liu; Rupak Bhakta; Emily Kryvorutsky; Yuanwei Zhang

doi:10.1364/ECBO.2025.S4A.2

Modulated optically computed phase microscopy for high-resolution, high-sensitivity label-free imaging

Xuan Liu
, Rupak Bhakta
, Emily Kryvorutsky
, Yuanwei Zhang

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

To study cell-nanoparticle interactions, we developed and validated the modulated optically computed phase microscopy technology which utilizes optical computation to perform Fourier transform and impose temporal modulation to achieve high resolution and high phase sensitivity.

Original language	English (US)
Title of host publication	European Conference on Biomedical Optics, ECBO 2025
Publisher	Optical Society of America
ISBN (Electronic)	9781557528001
DOIs	https://doi.org/10.1364/ECBO.2025.S4A.2
State	Published - 2025
Event	2025 European Conference on Biomedical Optics, ECBO 2025 - Munich, Germany Duration: Jun 22 2025 → Jun 26 2025

Publication series

Name	European Conference on Biomedical Optics, ECBO 2025

Conference

Conference	2025 European Conference on Biomedical Optics, ECBO 2025
Country/Territory	Germany
City	Munich
Period	6/22/25 → 6/26/25

All Science Journal Classification (ASJC) codes

Biomedical Engineering
Biomaterials
Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics

Access to Document

10.1364/ECBO.2025.S4A.2

Cite this

@inproceedings{d6a3620d95a34ab09607bced7154753b,

title = "Modulated optically computed phase microscopy for high-resolution, high-sensitivity label-free imaging",

abstract = "To study cell-nanoparticle interactions, we developed and validated the modulated optically computed phase microscopy technology which utilizes optical computation to perform Fourier transform and impose temporal modulation to achieve high resolution and high phase sensitivity.",

author = "Xuan Liu and Rupak Bhakta and Emily Kryvorutsky and Yuanwei Zhang",

note = "Publisher Copyright: {\textcopyright} 2025 The Author(s); 2025 European Conference on Biomedical Optics, ECBO 2025 ; Conference date: 22-06-2025 Through 26-06-2025",

year = "2025",

doi = "10.1364/ECBO.2025.S4A.2",

language = "English (US)",

series = "European Conference on Biomedical Optics, ECBO 2025",

publisher = "Optical Society of America",

booktitle = "European Conference on Biomedical Optics, ECBO 2025",

}

Liu, X, Bhakta, R, Kryvorutsky, E & Zhang, Y 2025, Modulated optically computed phase microscopy for high-resolution, high-sensitivity label-free imaging. in European Conference on Biomedical Optics, ECBO 2025. European Conference on Biomedical Optics, ECBO 2025, Optical Society of America, 2025 European Conference on Biomedical Optics, ECBO 2025, Munich, Germany, 6/22/25. https://doi.org/10.1364/ECBO.2025.S4A.2

Modulated optically computed phase microscopy for high-resolution, high-sensitivity label-free imaging. / Liu, Xuan; Bhakta, Rupak; Kryvorutsky, Emily et al.
European Conference on Biomedical Optics, ECBO 2025. Optical Society of America, 2025. (European Conference on Biomedical Optics, ECBO 2025).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Modulated optically computed phase microscopy for high-resolution, high-sensitivity label-free imaging

AU - Liu, Xuan

AU - Bhakta, Rupak

AU - Kryvorutsky, Emily

AU - Zhang, Yuanwei

PY - 2025

Y1 - 2025

N2 - To study cell-nanoparticle interactions, we developed and validated the modulated optically computed phase microscopy technology which utilizes optical computation to perform Fourier transform and impose temporal modulation to achieve high resolution and high phase sensitivity.

AB - To study cell-nanoparticle interactions, we developed and validated the modulated optically computed phase microscopy technology which utilizes optical computation to perform Fourier transform and impose temporal modulation to achieve high resolution and high phase sensitivity.

UR - https://www.scopus.com/pages/publications/105031899680

UR - https://www.scopus.com/pages/publications/105031899680#tab=citedBy

U2 - 10.1364/ECBO.2025.S4A.2

DO - 10.1364/ECBO.2025.S4A.2

M3 - Conference contribution

AN - SCOPUS:105031899680

T3 - European Conference on Biomedical Optics, ECBO 2025

BT - European Conference on Biomedical Optics, ECBO 2025

PB - Optical Society of America

T2 - 2025 European Conference on Biomedical Optics, ECBO 2025

Y2 - 22 June 2025 through 26 June 2025

ER -

Modulated optically computed phase microscopy for high-resolution, high-sensitivity label-free imaging

Abstract

Publication series

Conference

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this