Molecular communication and signaling in human cells

I. Habibi, A. Abdi, E. S. Emamian

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Signaling networks in human cells convey signals from the cell membrane to specific target molecules via biochemical interactions, to control a variety of cellular functions. We have modeled signaling networks as communication channels where molecules communicate with each other to transfer signals. We have defined and computed the fundamental parameters of transmission error probability and signaling capacity in signaling networks. This systematic approach can be used to understand how cell signaling errors and malfunctioning molecules may contribute to the development of complex human disorders with unknown molecular bases.

Original languageEnglish (US)
Title of host publicationConference Record of the 49th Asilomar Conference on Signals, Systems and Computers, ACSSC 2015
EditorsMichael B. Matthews
PublisherIEEE Computer Society
Pages128-132
Number of pages5
ISBN (Electronic)9781467385763
DOIs
StatePublished - Feb 26 2016
Event49th Asilomar Conference on Signals, Systems and Computers, ACSSC 2015 - Pacific Grove, United States
Duration: Nov 8 2015Nov 11 2015

Publication series

NameConference Record - Asilomar Conference on Signals, Systems and Computers
Volume2016-February
ISSN (Print)1058-6393

Other

Other49th Asilomar Conference on Signals, Systems and Computers, ACSSC 2015
Country/TerritoryUnited States
CityPacific Grove
Period11/8/1511/11/15

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Computer Networks and Communications

Keywords

  • capacity
  • communication channels
  • human disease
  • molecular networks
  • signal transduction
  • signaling error
  • systems biology
  • transmission error probability

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