TY - JOUR
T1 - Monte Carlo simulation of light-tissue interaction
T2 - Three-dimensional simulation for trans-illumination-based imaging of skin lesions
AU - Patwardhan, Sachin V.
AU - Dhawan, Atam P.
AU - Relue, Patricia A.
N1 - Funding Information:
Manuscript received May 16, 2003; revised November 14, 2004. This work was supported in part by the Whitaker Foundation under Research Grant RG-99-0127. Asterisk indicates corresponding author. S. V. Patwardhan is with the Department of Electrical and Computer Engineering, New Jersey Institute of Technology, Newark, NJ 07102 USA. *A. P. Dhawan is with the Department of Electrical and Computer Engineering, New Jersey Institute of Technology, 323 M. L. King Blvd., Newark, NJ 07102 USA (e-mail: [email protected]). P. A. Relue is with the Department of Bio-engineering, University of Toledo, Toledo, OH 43606 USA. Digital Object Identifier 10.1109/TBME.2005.847546
PY - 2005/7
Y1 - 2005/7
N2 - Three-dimensional, voxel-based, and wavelength-dependent skin lesion models are developed and simulated using Monte Carlo techniques. The optical geometry of the Nevoscope with trans-illumination is used in the simulations for characterizing the lesion thickness. Based on the correlation analysis between the lesion thickness and the diffuse reflectance, optical wavelengths are selected for multispectral imaging of skin lesions using the Nevoscope. Tissue optical properties reported by various researchers are compiled together to form a voxel library. Tissue models used in the simulations are developed using the voxel library which offers flexibility in updating the optical properties and adding new media types into the models independent of the Monte Carlo simulation code.
AB - Three-dimensional, voxel-based, and wavelength-dependent skin lesion models are developed and simulated using Monte Carlo techniques. The optical geometry of the Nevoscope with trans-illumination is used in the simulations for characterizing the lesion thickness. Based on the correlation analysis between the lesion thickness and the diffuse reflectance, optical wavelengths are selected for multispectral imaging of skin lesions using the Nevoscope. Tissue optical properties reported by various researchers are compiled together to form a voxel library. Tissue models used in the simulations are developed using the voxel library which offers flexibility in updating the optical properties and adding new media types into the models independent of the Monte Carlo simulation code.
KW - Correlation analysis
KW - Multispectral imaging
KW - Nevoscope
KW - Skin lesion models
KW - Voxel-based Monte Carlo simulation
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U2 - 10.1109/TBME.2005.847546
DO - 10.1109/TBME.2005.847546
M3 - Article
C2 - 16041986
AN - SCOPUS:21844465713
SN - 0018-9294
VL - 52
SP - 1227
EP - 1236
JO - IEEE Transactions on Biomedical Engineering
JF - IEEE Transactions on Biomedical Engineering
IS - 7
ER -