Multimodal gadolinium-enriched DNA-gold nanoparticle conjugates for cellular imaging

Ying Song, Xiaoyang Xu, Keith W. MacRenaris, Xue Qing Zhang, Chad A. Mirkin, Thomas J. Meade

Research output: Contribution to journalArticlepeer-review

145 Scopus citations

Abstract

Conjugate agent: A GdIII enriched DNAAuNP conjugate for intracellular magnetic resonance and fluorescence imaging is reported. The agent exhibits high relaxivity per particle and high cell uptake properties that provide a means to image and map small cell populations.

Original languageEnglish (US)
Pages (from-to)9143-9147
Number of pages5
JournalAngewandte Chemie - International Edition
Volume48
Issue number48
DOIs
StatePublished - Nov 16 2009
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

Keywords

  • DNA
  • Fluorescence imaging
  • Gadolinium
  • Gold nanoparticles
  • Magnetic resonance imaging

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