TY - JOUR
T1 - Nature of linear spectral properties and fast electronic relaxations in green fluorescent pyrrolo[3,4-c]pyridine derivative
AU - Bashmakova, Nataliia V.
AU - Shaydyuk, Yevgeniy O.
AU - Dmytruk, Andriy M.
AU - Świergosz, Tomasz
AU - Kachkovsky, Olexiy D.
AU - Belfield, Kevin D.
AU - Bondar, Mykhailo V.
AU - Kasprzyk, Wiktor
N1 - Funding Information:
Funding: This research was financed by the Polish National Science Centre for years 2018–2021; SONATINA No. UMO-2018/28/C/ST5/00461, Polish National Agency for Academic Exchange (The Bekker Program No. PPN/BEK/2018/1/00460/U/00001). The authors thank the employees of the NASU Center for collective use of equipment “Laser femtosecond complex” at the Institute of Physics NAS Ukraine. This work is supported in part by the National Academy of Sciences of Ukraine (grants VC/188 and V/204). KDB acknowledges support from the US National Science Foundation (CHE-1726345) and the Becton-Dickinson Research Professorship.
Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/6/1
Y1 - 2021/6/1
N2 - The electronic nature of 4-hydroxy-1H-pyrrolo[3,4-c]pyridine-1,3,6(2H,5H)-trione (HPPT) was comprehensively investigated in liquid media at room temperature using steady-state and time-resolved femtosecond transient absorption spectroscopic techniques. The analysis of the linear photophysical and photochemical parameters of HPPT, including steady-state absorption, fluorescence and excitation anisotropy spectra, along with the lifetimes of fluorescence emission and photodecomposition quantum yields, revealed the nature of its large Stokes shift, specific changes in the permanent dipole moments under electronic excitation, weak dipole transitions with partially anisotropic character, and high photostability. Transient absorption spectra of HPPT were obtained with femtosecond resolution and no characteristic solvate relaxation processes in protic (methanol) solvent were revealed. Efficient light amplification (gain) was observed in the fluorescence spectral range of HPPT, but no super-luminescence and lasing phenomena were detected. The electronic structure of HPPT was also analyzed with quantum-chemical calculations using a DFT/B3LYP method and good agreement with experimental data was shown. The development and investigation of new pyrrolo[3,4-c]pyridine derivatives are important due to their promising fluorescent properties and potential for use in physiological applications.
AB - The electronic nature of 4-hydroxy-1H-pyrrolo[3,4-c]pyridine-1,3,6(2H,5H)-trione (HPPT) was comprehensively investigated in liquid media at room temperature using steady-state and time-resolved femtosecond transient absorption spectroscopic techniques. The analysis of the linear photophysical and photochemical parameters of HPPT, including steady-state absorption, fluorescence and excitation anisotropy spectra, along with the lifetimes of fluorescence emission and photodecomposition quantum yields, revealed the nature of its large Stokes shift, specific changes in the permanent dipole moments under electronic excitation, weak dipole transitions with partially anisotropic character, and high photostability. Transient absorption spectra of HPPT were obtained with femtosecond resolution and no characteristic solvate relaxation processes in protic (methanol) solvent were revealed. Efficient light amplification (gain) was observed in the fluorescence spectral range of HPPT, but no super-luminescence and lasing phenomena were detected. The electronic structure of HPPT was also analyzed with quantum-chemical calculations using a DFT/B3LYP method and good agreement with experimental data was shown. The development and investigation of new pyrrolo[3,4-c]pyridine derivatives are important due to their promising fluorescent properties and potential for use in physiological applications.
KW - Femtosecond transient absorption spectroscopy
KW - Linear spectral properties
KW - Pyrrolo[3,4-c]pyridine derivative
KW - Quantum chemical analysis
UR - http://www.scopus.com/inward/record.url?scp=85106398019&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85106398019&partnerID=8YFLogxK
U2 - 10.3390/ijms22115592
DO - 10.3390/ijms22115592
M3 - Article
C2 - 34070488
AN - SCOPUS:85106398019
SN - 1661-6596
VL - 22
JO - International Journal of Molecular Sciences
JF - International Journal of Molecular Sciences
IS - 11
M1 - 5592
ER -