New screening methodology for selection of polymeric matrices for transdermal drug delivery devices

R. Falcone, M. Jaffe, N. M. Ravindra

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Transdermal drug delivery systems, such as patches, are viewed as one the best technologies that enhance greater patient compliance thus providing the desired therapeutic results. However, one of the main challenges is to find the right polymeric matrix that will provide the desired active therapeutic concentration. This is usually accomplished empirically and is not always the effective approach. In this study, the authors describe a predictive screening methodology based on material parameters to identify materials that will accomplish therapeutic targets.

Original languageEnglish (US)
Pages (from-to)65-75
Number of pages11
JournalBioinspired, Biomimetic and Nanobiomaterials
Volume2
Issue number2
DOIs
StatePublished - Jun 2013

All Science Journal Classification (ASJC) codes

  • Biomaterials
  • General Engineering

Keywords

  • Controlled delivery
  • Diffusion
  • Nicotine
  • Patches
  • Physical property model
  • Transdermal drug delivery

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