NIR light penetration depth in the rat peripheral nerve and brain cortex

Ammar Abdo, Mesut Sahin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

16 Scopus citations

Abstract

Near infrared (NIR) light energy has been used in medical applications both for diagnostic and treatment purposes. A priory knowledge of optical tissue properties is necessary in these applications; not only of human but also in animals for testing of devices. However, published data on the optical properties of neural tissue in rodents are rare. The aim of this study was to measure the penetration depth of light into the rat peripheral nerve and brain cortex at NIR wavelengths. Penetration depth was calculated from measurements of transmitted light for various thicknesses of the neural tissue. We found the penetration depth in the rat sciatic nerve to be 0.35±0.023mm and in the white matter 0.35±0.026mm. The penetration depth of the gray matter was 0.41±0.029mm. Compared to the data reported in literature for the human brain, the rat peripheral and the brain cortex attenuate the NIR light much more strongly.

Original languageEnglish (US)
Title of host publication29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
Pages1723-1725
Number of pages3
DOIs
StatePublished - 2007
Event29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 - Lyon, France
Duration: Aug 23 2007Aug 26 2007

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ISSN (Print)0589-1019

Other

Other29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
CountryFrance
CityLyon
Period8/23/078/26/07

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Keywords

  • Near infrared light
  • Penetration depth
  • Reflectance
  • Transmittance

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