Novel fluorescent biosensor for pathogenic toxins using cyclic polypeptide conjugates

Omowunmi A. Sadik; Fei Yan

doi:10.1039/b316057b

Novel fluorescent biosensor for pathogenic toxins using cyclic polypeptide conjugates

Omowunmi A. Sadik, Fei Yan

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

This work describes a two-step conjugate synthesis of a new fluorescent analog of microcystin-LR and its subsequent utilization for the development of an optical biosensor for cyanobacteria toxins. The biosensor concept is based on the competitive binding between the native microcystin and its fluorescent analog at immobilized alkaline phosphatase enzymes.

Original language	English (US)
Pages (from-to)	1136-1137
Number of pages	2
Journal	Chemical Communications
Volume	4
Issue number	9
DOIs	https://doi.org/10.1039/b316057b
State	Published - 2004
Externally published	Yes

All Science Journal Classification (ASJC) codes

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b316057b

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title = "Novel fluorescent biosensor for pathogenic toxins using cyclic polypeptide conjugates",

abstract = "This work describes a two-step conjugate synthesis of a new fluorescent analog of microcystin-LR and its subsequent utilization for the development of an optical biosensor for cyanobacteria toxins. The biosensor concept is based on the competitive binding between the native microcystin and its fluorescent analog at immobilized alkaline phosphatase enzymes.",

author = "Sadik, {Omowunmi A.} and Fei Yan",

year = "2004",

doi = "10.1039/b316057b",

language = "English (US)",

volume = "4",

pages = "1136--1137",

journal = "Chemical Communications",

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AU - Sadik, Omowunmi A.

AU - Yan, Fei

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AB - This work describes a two-step conjugate synthesis of a new fluorescent analog of microcystin-LR and its subsequent utilization for the development of an optical biosensor for cyanobacteria toxins. The biosensor concept is based on the competitive binding between the native microcystin and its fluorescent analog at immobilized alkaline phosphatase enzymes.

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DO - 10.1039/b316057b

M3 - Article

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AN - SCOPUS:2442691415

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SP - 1136

EP - 1137

JO - Chemical Communications

JF - Chemical Communications

IS - 9

ER -

Novel fluorescent biosensor for pathogenic toxins using cyclic polypeptide conjugates

Abstract

All Science Journal Classification (ASJC) codes

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