Novel lysosomal targeting two-photon fluorescence probe based on fluorene difluoroboron β-diketonate

Andrew Frazer; Alma R. Morales; Adam Woodward; Simon Tang; Kevin D. Belfield

doi:10.1364/omp.2013.mth1c.3

Novel lysosomal targeting two-photon fluorescence probe based on fluorene difluoroboron β-diketonate

Andrew Frazer, Alma R. Morales, Adam Woodward, Simon Tang, Kevin D. Belfield

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We report the synthesis and photophysical characteristics of a two photon fluorescent (2PF) fluorene-based pyridyl difluoroboron-β-diketonate, which when incubated in HCT 116 cells shows superior accumulation in lysosomes in both isolate and encapsulated pluronics.

Original language	English (US)
Title of host publication	Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013
Publisher	Optical Society of America (OSA)
Pages	MTh1C.3
ISBN (Print)	9781557529664
DOIs	https://doi.org/10.1364/omp.2013.mth1c.3
State	Published - 2013
Externally published	Yes
Event	Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013 - Waikoloa Beach, HI, United States Duration: Apr 14 2013 → Apr 18 2013

Publication series

Name	Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013

Other

Other	Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013
Country/Territory	United States
City	Waikoloa Beach, HI
Period	4/14/13 → 4/18/13

All Science Journal Classification (ASJC) codes

Radiology Nuclear Medicine and imaging
Atomic and Molecular Physics, and Optics

Access to Document

10.1364/omp.2013.mth1c.3

Cite this

Frazer, A., Morales, A. R., Woodward, A., Tang, S., & Belfield, K. D. (2013). Novel lysosomal targeting two-photon fluorescence probe based on fluorene difluoroboron β-diketonate. In Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013 (pp. MTh1C.3). (Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013). Optical Society of America (OSA). https://doi.org/10.1364/omp.2013.mth1c.3

@inproceedings{1de696c3eeaa4df4912177dcfce9d6c3,

title = "Novel lysosomal targeting two-photon fluorescence probe based on fluorene difluoroboron β-diketonate",

abstract = "We report the synthesis and photophysical characteristics of a two photon fluorescent (2PF) fluorene-based pyridyl difluoroboron-β-diketonate, which when incubated in HCT 116 cells shows superior accumulation in lysosomes in both isolate and encapsulated pluronics.",

author = "Andrew Frazer and Morales, {Alma R.} and Adam Woodward and Simon Tang and Belfield, {Kevin D.}",

year = "2013",

doi = "10.1364/omp.2013.mth1c.3",

language = "English (US)",

isbn = "9781557529664",

series = "Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013",

publisher = "Optical Society of America (OSA)",

pages = "MTh1C.3",

booktitle = "Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013",

note = "Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013 ; Conference date: 14-04-2013 Through 18-04-2013",

}

Frazer, A, Morales, AR, Woodward, A, Tang, S & Belfield, KD 2013, Novel lysosomal targeting two-photon fluorescence probe based on fluorene difluoroboron β-diketonate. in Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013. Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013, Optical Society of America (OSA), pp. MTh1C.3, Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013, Waikoloa Beach, HI, United States, 4/14/13. https://doi.org/10.1364/omp.2013.mth1c.3

Novel lysosomal targeting two-photon fluorescence probe based on fluorene difluoroboron β-diketonate. / Frazer, Andrew; Morales, Alma R.; Woodward, Adam et al.
Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013. Optical Society of America (OSA), 2013. p. MTh1C.3 (Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Novel lysosomal targeting two-photon fluorescence probe based on fluorene difluoroboron β-diketonate

AU - Frazer, Andrew

AU - Morales, Alma R.

AU - Woodward, Adam

AU - Tang, Simon

AU - Belfield, Kevin D.

PY - 2013

Y1 - 2013

N2 - We report the synthesis and photophysical characteristics of a two photon fluorescent (2PF) fluorene-based pyridyl difluoroboron-β-diketonate, which when incubated in HCT 116 cells shows superior accumulation in lysosomes in both isolate and encapsulated pluronics.

AB - We report the synthesis and photophysical characteristics of a two photon fluorescent (2PF) fluorene-based pyridyl difluoroboron-β-diketonate, which when incubated in HCT 116 cells shows superior accumulation in lysosomes in both isolate and encapsulated pluronics.

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DO - 10.1364/omp.2013.mth1c.3

M3 - Conference contribution

AN - SCOPUS:84887551621

SN - 9781557529664

T3 - Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013

SP - MTh1C.3

BT - Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013

PB - Optical Society of America (OSA)

T2 - Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013

Y2 - 14 April 2013 through 18 April 2013

ER -

Frazer A, Morales AR, Woodward A, Tang S, Belfield KD. Novel lysosomal targeting two-photon fluorescence probe based on fluorene difluoroboron β-diketonate. In Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013. Optical Society of America (OSA). 2013. p. MTh1C.3. (Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013). doi: 10.1364/omp.2013.mth1c.3

Novel lysosomal targeting two-photon fluorescence probe based on fluorene difluoroboron β-diketonate

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All Science Journal Classification (ASJC) codes

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