Novel lysosomal targeting two-photon fluorescence probe based on fluorene difluoroboron β-diketonate

Andrew Frazer, Alma R. Morales, Adam Woodward, Simon Tang, Kevin D. Belfield

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We report the synthesis and photophysical characteristics of a two photon fluorescent (2PF) fluorene-based pyridyl difluoroboron-β-diketonate, which when incubated in HCT 116 cells shows superior accumulation in lysosomes in both isolate and encapsulated pluronics.

Original languageEnglish (US)
Title of host publicationOptical Molecular Probes, Imaging and Drug Delivery, OMP 2013
PublisherOptical Society of America (OSA)
PagesMTh1C.3
ISBN (Print)9781557529664
DOIs
StatePublished - 2013
Externally publishedYes
EventOptical Molecular Probes, Imaging and Drug Delivery, OMP 2013 - Waikoloa Beach, HI, United States
Duration: Apr 14 2013Apr 18 2013

Publication series

NameOptical Molecular Probes, Imaging and Drug Delivery, OMP 2013

Other

OtherOptical Molecular Probes, Imaging and Drug Delivery, OMP 2013
CountryUnited States
CityWaikoloa Beach, HI
Period4/14/134/18/13

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Atomic and Molecular Physics, and Optics

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