Organic reactions of ionic intermediates promoted by atmospheric-pressure thermal activation

Hao Chen; Livia S. Eberlin; Marcela Nefliu; Rodinei Augusti; R. Graham Cooks

doi:10.1002/anie.200800072

Organic reactions of ionic intermediates promoted by atmospheric-pressure thermal activation

Hao Chen, Livia S. Eberlin, Marcela Nefliu, Rodinei Augusti, R. Graham Cooks

Research output: Contribution to journal › Article › peer-review

66 Scopus citations

Abstract

(Chemical Equation Presented) A mild-mannered process: Novel methodology, in which electrosonic spray ionization (ESSI, see schematic diagram) is used as the proton source, has been used to generate ionic reaction intermediates whose conversion into products can be promoted by atmospheric-pressure thermal activation. Reactions performed under these mild conditions include Borsche-Drechsel cyclization, Fischer indole synthesis, and pinacol rearrangement.

Original language	English (US)
Pages (from-to)	3422-3425
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	47
Issue number	18
DOIs	https://doi.org/10.1002/anie.200800072
State	Published - Apr 21 2008
Externally published	Yes

All Science Journal Classification (ASJC) codes

Catalysis
General Chemistry

Keywords

Green chemistry
Mass spectrometry
Protonation
Reaction intermediates
Synthetic methods

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10.1002/anie.200800072

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AU - Chen, Hao

AU - Eberlin, Livia S.

AU - Nefliu, Marcela

AU - Augusti, Rodinei

AU - Cooks, R. Graham

PY - 2008/4/21

Y1 - 2008/4/21

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KW - Green chemistry

KW - Mass spectrometry

KW - Protonation

KW - Reaction intermediates

KW - Synthetic methods

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ER -

Organic reactions of ionic intermediates promoted by atmospheric-pressure thermal activation

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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