(Chemical Equation Presented) A mild-mannered process: Novel methodology, in which electrosonic spray ionization (ESSI, see schematic diagram) is used as the proton source, has been used to generate ionic reaction intermediates whose conversion into products can be promoted by atmospheric-pressure thermal activation. Reactions performed under these mild conditions include Borsche-Drechsel cyclization, Fischer indole synthesis, and pinacol rearrangement.
All Science Journal Classification (ASJC) codes
- Green chemistry
- Mass spectrometry
- Reaction intermediates
- Synthetic methods