The osteogenic activity of human mesenchymal stem cells (MSCs) on various hydroxyapatite/β-tricalcium phosphate (HA/TCP) composition in vivo was examined. MSC-loaded matrices and cell-free matrices were implanted subcutaneously in SCID mice. Implants were harvested at 6 and 12 weeks and were processed for decalcified paraffin histology. The results demonstrate the potential of using faster resorbing ceramics, in combination with MSCs for bone regeneration.
All Science Journal Classification (ASJC) codes
- Biomedical Engineering