Patient ADE Risk Prediction through Hierarchical Time-Aware Neural Network Using Claim Codes

Jinhe Shi, Xiangyu Gao, Chenyu Ha, Yage Wang, Guodong Gao, Yi Chen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Adverse drug events (ADEs) are a serious health problem that can be life-threatening. While a lot of work on detecting correlation between a drug and an ADE, limited studies have been conducted on personalized ADE risk prediction. Avoiding the drugs with high likelihood of causing severe ADEs helps physicians to provide safer treatments to patients. The goal of this study is to assess personalized ADE risks that a target drug may induce on a target patient, based on patient medical history recorded in claim codes, which provide information about diagnosis, drugs taken, related medical supplies besides billing information. We developed a HTNNR model (Hierarchical Time-aware Neural Network for ADE Risk) that captures characteristics of claim codes and their relationship. Eempirical evaluation shows that the proposed HTNNR model substantially outperforms the comparison methods.

Original languageEnglish (US)
Title of host publicationProceedings - 2020 IEEE International Conference on Big Data, Big Data 2020
EditorsXintao Wu, Chris Jermaine, Li Xiong, Xiaohua Tony Hu, Olivera Kotevska, Siyuan Lu, Weijia Xu, Srinivas Aluru, Chengxiang Zhai, Eyhab Al-Masri, Zhiyuan Chen, Jeff Saltz
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1388-1393
Number of pages6
ISBN (Electronic)9781728162515
DOIs
StatePublished - Dec 10 2020
Event8th IEEE International Conference on Big Data, Big Data 2020 - Virtual, Atlanta, United States
Duration: Dec 10 2020Dec 13 2020

Publication series

NameProceedings - 2020 IEEE International Conference on Big Data, Big Data 2020

Conference

Conference8th IEEE International Conference on Big Data, Big Data 2020
CountryUnited States
CityVirtual, Atlanta
Period12/10/2012/13/20

All Science Journal Classification (ASJC) codes

  • Computer Networks and Communications
  • Information Systems
  • Information Systems and Management
  • Safety, Risk, Reliability and Quality

Keywords

  • Adverse Drug Events
  • Claim Codes
  • Neural Networks
  • Personalized Risk Assessment

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