Abstract
Manufacturing of drug delivery systems through the extrusion process is of great interest in academia and pharmaceutical industry alike. Even though significant amount of research has been conducted in this field, there are still many challenges to be addressed such as: thermal stability of drugs, difficult downstream handling of extrudates and high density of the extrudates. Recently, the foaming process is being seen as an answer for some of these problems. This paper reviews the role of polymeric foams in the manufacture of oral drug delivery systems. A case study analyzing the influence of foaming on the dissolution profile of a polymeric excipient in water is discussed in more detail.
| Original language | English (US) |
|---|---|
| State | Published - 2011 |
| Event | 9th International Conference on Foam Processing and Technology, FOAMS 2011 - Iselin, NJ, United States Duration: Sep 14 2011 → Sep 15 2011 |
Other
| Other | 9th International Conference on Foam Processing and Technology, FOAMS 2011 |
|---|---|
| Country/Territory | United States |
| City | Iselin, NJ |
| Period | 9/14/11 → 9/15/11 |
All Science Journal Classification (ASJC) codes
- Fluid Flow and Transfer Processes
Keywords
- Foams
- HME
- Pharmaceuticals