@inproceedings{334b9d6240f24d879569c1c90a02e19b,
title = "Quality Assurance of Concept Roles in the National Cancer Institute thesaurus",
abstract = "Ontologies are integral components of many health information processing environments. Hence, quality assurance (QA) of the conceptual content of any ontology is essential. A methodology for facilitating the identification and correction of a kind of error called 'missing-role error' for ontology concepts is presented. Specifically, being a member of the 'null-role set' is used as an indicator that missing-role errors are likely. Our QA methodology was applied to the Biological Process hierarchy, one of the hierarchies of the National Cancer Institute thesaurus (NCIt), a prominent ontology in the biomedical domain. Two hypotheses pertaining to the effectiveness of our QA approach were investigated. Many missing-role errors were discovered and confirmed in our analysis. In comparison to a control sample, our QA approach yielded a statistically significant number of concepts with missing-role errors, confirming our two hypotheses. QA is a critical part of an ontology's life-cycle, and automated or semi-automated tools for supporting this process are invaluable. The presented approach is a useful addition to the arsenal of tools available to QA personnel.",
keywords = "National Cancer Institute thesaurus, Ontology, Ontology Modeling, Quality Assurance, Role Error",
author = "Ling Zheng and Yan Chen and Yehoshua Perl and Michael Halper and James Geller and {De Coronado}, Sherri",
note = "Publisher Copyright: {\textcopyright} 2018 IEEE.; 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018 ; Conference date: 03-12-2018 Through 06-12-2018",
year = "2019",
month = jan,
day = "21",
doi = "10.1109/BIBM.2018.8621277",
language = "English (US)",
series = "Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "2001--2008",
editor = "Harald Schmidt and David Griol and Haiying Wang and Jan Baumbach and Huiru Zheng and Zoraida Callejas and Xiaohua Hu and Julie Dickerson and Le Zhang",
booktitle = "Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018",
address = "United States",
}