Rational design of fiber forming supramolecular structures

Vivek A. Kumar, Benjamin K. Wang, Satoko M. Kanahara

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Recent strides in the development of multifunctional synthetic biomimetic materials through the self-assembly of multi-domain peptides and proteins over the past decade have been realized. Such engineered systems have wide-ranging application in bioengineering and medicine. This review focuses on fundamental fiber forming α-helical coiled-coil peptides, peptide amphiphiles, and amyloid-based self-assembling peptides; followed by higher order collagen- and elastin-mimetic peptides with an emphasis on chemical / biological characterization and biomimicry.

Original languageEnglish (US)
Pages (from-to)899-908
Number of pages10
JournalExperimental Biology and Medicine
Issue number9
StatePublished - May 2016
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Biochemistry, Genetics and Molecular Biology


  • Tissue engineering
  • elastin-mimetic peptides
  • peptide amphiphiles
  • peptide chemistry
  • supramolecular chemistry


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