Abstract
Recent strides in the development of multifunctional synthetic biomimetic materials through the self-assembly of multi-domain peptides and proteins over the past decade have been realized. Such engineered systems have wide-ranging application in bioengineering and medicine. This review focuses on fundamental fiber forming α-helical coiled-coil peptides, peptide amphiphiles, and amyloid-based self-assembling peptides; followed by higher order collagen- and elastin-mimetic peptides with an emphasis on chemical / biological characterization and biomimicry.
Original language | English (US) |
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Pages (from-to) | 899-908 |
Number of pages | 10 |
Journal | Experimental Biology and Medicine |
Volume | 241 |
Issue number | 9 |
DOIs | |
State | Published - May 2016 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- General Biochemistry, Genetics and Molecular Biology
Keywords
- Tissue engineering
- elastin-mimetic peptides
- peptide amphiphiles
- peptide chemistry
- supramolecular chemistry