Rational design of fiber forming supramolecular structures

Vivek A. Kumar, Benjamin K. Wang, Satoko M. Kanahara

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Recent strides in the development of multifunctional synthetic biomimetic materials through the self-assembly of multi-domain peptides and proteins over the past decade have been realized. Such engineered systems have wide-ranging application in bioengineering and medicine. This review focuses on fundamental fiber forming α-helical coiled-coil peptides, peptide amphiphiles, and amyloid-based self-assembling peptides; followed by higher order collagen- and elastin-mimetic peptides with an emphasis on chemical / biological characterization and biomimicry.

Original languageEnglish (US)
Pages (from-to)899-908
Number of pages10
JournalExperimental Biology and Medicine
Volume241
Issue number9
DOIs
StatePublished - May 2016
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Keywords

  • Tissue engineering
  • elastin-mimetic peptides
  • peptide amphiphiles
  • peptide chemistry
  • supramolecular chemistry

Fingerprint Dive into the research topics of 'Rational design of fiber forming supramolecular structures'. Together they form a unique fingerprint.

Cite this