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Relational Graph Convolutional Network with BERT Embeddings for Ontology Relationship Classification

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

SNOMED CT is one of the largest and most widely used medical ontologies. It is a collection of medical concepts with a large number of relationships between concept pairs. One of the most laborious tasks for SNOMED CT curators is placing concepts in the correct hierarchical positions with accurate relationships. We present a method that utilizes domain-specific BERT models integrated with a Relational Graph Convolutional Network (RGCN) for classifying the relationships between SNOMED CT concept pairs. We generate node embeddings using five domain-specific BERT models, BioBERT, ClinicalBERT, SapBERT, SciBERT, and BioMedBERT, and feed them individually into an RGCN model for relationship classification. We apply a three-layer RGCN to capture and utilize the graph-structured dependencies among concepts, enabling the model to propagate relational information across connected nodes before performing classification. We demonstrate that each BERT embedding integrated with RGCN outperforms both the Message-Passing Neural Network (MPNN) and Neural Network (NN) baselines. Our work shows that SapBERT-RGCN achieves the best performance across all tested encoders, with an accuracy of 0.9394 and an F1-weighted score of 0.9412. Compared to the best-performing domain-specific BERT-NN baseline, this is a 4% accuracy gain with a notable improvement of F1-macro.

Original languageEnglish (US)
Title of host publicationOpening the Personal Gate between Technology and Health Care - Proceedings of MIE 2026
EditorsMaria Hagglund, Lars Lindskold, Lenka Lhotska, Sara Marceglia, Enea Parimbelli, Lucia Sacchi, Paolo Soda, Lacramioara Stoicu-Tivadar, Pierangelo Veltri, Patrizia Vizza, Mauro Giacomini, Jaime Delgado, Theodoros N. Arvanitis, Elisavet Andrikopoulou, Arriel Benis, Gabriella Balestra, Riccardo Bellazzi, Parisis G. Gallos, Roberto Gatta, Daniele Roberto Giacobbe, Noemi Giordano
PublisherIOS Press BV
Pages2430-2434
Number of pages5
ISBN (Electronic)9781643686615
DOIs
StatePublished - May 21 2026
Event36th Medical Informatics Europe Conference, MIE 2026 - Genoa, Italy
Duration: May 25 2026May 28 2026

Publication series

NameStudies in Health Technology and Informatics
Volume336
ISSN (Print)0926-9630
ISSN (Electronic)1879-8365

Conference

Conference36th Medical Informatics Europe Conference, MIE 2026
Country/TerritoryItaly
CityGenoa
Period5/25/265/28/26

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Health Informatics
  • Health Information Management

Keywords

  • Domain-Specific BERTs
  • Relational Graph Neural Network
  • SNOMED CT

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