Review paper: Processing aspects of hot melt extrusion in pharmaceutical applications

Huiju Liu, Peng Wang, Marino Xanthos, Linjie Zhu, Costas Gogos

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

Applying extrusion technology to drug manufacturing received increasing attention in the last two decades. Extrusion technology has the potential of replacing current Pharmaceuticals manufacturing methods due to the advantages such as the elimination of solvent and the continuous and consistent high throughput. This article presents a brief review of Hot Melt Extrusion (HME) from polymer processing perspective, concentrating on mixing, material degradation and process analytical technology.

Original languageEnglish (US)
Title of host publication67th Annual Technical Conference of the Society of Plastics Engineers 2009, ANTEC 2009
Pages2370-2375
Number of pages6
StatePublished - Nov 26 2009
Event67th Annual Technical Conference of the Society of Plastics Engineers 2009, ANTEC 2009 - Chicago, IL, United States
Duration: Jun 22 2009Jun 24 2009

Publication series

NameAnnual Technical Conference - ANTEC, Conference Proceedings
Volume4

Other

Other67th Annual Technical Conference of the Society of Plastics Engineers 2009, ANTEC 2009
CountryUnited States
CityChicago, IL
Period6/22/096/24/09

All Science Journal Classification (ASJC) codes

  • Chemical Engineering(all)
  • Polymers and Plastics

Keywords

  • Hot melt extrusion
  • Mixing
  • Pharmaceutical

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