Robust motion tracking based on adaptive speckle decorrelation analysis of OCT signal

Yuewen Wang, Yahui Wang, Ali Akansu, Kevin D. Belfield, Basil Hubbi, Xuan Liu

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Speckle decorrelation analysis of optical coherence tomography (OCT) signal has been used in motion tracking. In our previous study, we demonstrated that cross-correlation coefficient (XCC) between Ascans had an explicit functional dependency on the magnitude of lateral displacement (δx). In this study, we evaluated the sensitivity of speckle motion tracking using the derivative of function XCC(δx) on variable δx. We demonstrated the magnitude of the derivative can be maximized. In other words, the sensitivity of OCT speckle tracking can be optimized by using signals with appropriate amount of decorrelation for XCC calculation. Based on this finding, we developed an adaptive speckle decorrelation analysis strategy to achieve motion tracking with optimized sensitivity. Briefly, we used subsequently acquired Ascans and Ascans obtained with larger time intervals to obtain multiple values of XCC and chose the XCC value that maximized motion tracking sensitivity for displacement calculation. Instantaneous motion speed can be calculated by dividing the obtained displacement with time interval between Ascans involved in XCC calculation. We implemented the above-described algorithm in real-time using graphic processing unit (GPU) and demonstrated its effectiveness in reconstructing distortion-free OCT images using data obtained from a manually scanned OCT probe. The adaptive speckle tracking method was validated in manually scanned OCT imaging, on phantom as well as in vivo skin tissue.

Original languageEnglish (US)
Article number247422
Pages (from-to)4302-4316
Number of pages15
JournalBiomedical Optics Express
Issue number11
StatePublished - Oct 8 2015

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Atomic and Molecular Physics, and Optics


  • Motion detection
  • Optical coherence tomography
  • Scanners
  • Speckle


Dive into the research topics of 'Robust motion tracking based on adaptive speckle decorrelation analysis of OCT signal'. Together they form a unique fingerprint.

Cite this