Abstract
This paper deals with the long-time behavior of solutions of nonlinear reaction-diffusion equations describing formation of morphogen gradients, the concentration fields of molecules acting as spatial regulators of cell differentiation in developing tissues. For the considered class of models, we establish existence of a new type of ultra-singular self-similar solutions. These solutions arise as limits of the solutions of the initial value problem with zero initial data and infinitely strong source at the boundary. We prove existence and uniqueness of such solutions in the suitable weighted energy spaces. Moreover, we prove that the obtained self-similar solutions are the long-time limits of the solutions of the initial value problem with zero initial data and a time-independent boundary source.
Original language | English (US) |
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Pages (from-to) | 767-780 |
Number of pages | 14 |
Journal | Networks and Heterogeneous Media |
Volume | 7 |
Issue number | 4 |
DOIs | |
State | Published - 2012 |
All Science Journal Classification (ASJC) codes
- Statistics and Probability
- General Engineering
- Computer Science Applications
- Applied Mathematics
Keywords
- Morphogen gradients
- Nonlinear diffusion equation
- Self-similarity