An unexpected ligand effect was discovered in the silver(I)-catalyzed alkyne activation. For both aldehyde-alkyne-amine (A3) condensation and intermolecular alkyne hydroamination, the type B complex (P:Ag=1:1) effectively promoted the reaction, while no reaction occurred with either no ligand or excess ligands under the identical conditions.
All Science Journal Classification (ASJC) codes
- Organic Chemistry
- alkyne-aldehyde-amine condensation
- ligand effect
- silver catalysis