Spatial coordinate corrected motion tracking for optical coherence elastography

Xuan Liu, Yuwei Liu, Basil Hubbi, Xianlian Zhou, Stephen Peters

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We develop a spatial coordinate corrected (SCC) motion tracking method for optical coherence elastography. SCC motion tracking refers the instantaneous velocity field extracted from optical coherence tomography (OCT) data to the laboratory coordinate system and accurately reconstructs the displacement field established during the mechanical excitation (compression) process. We acquired image data from compression OCE experiments on human breast tissue specimens, and reconstructed the displacement field through Doppler analysis of OCT data. Our results suggested that SCC tracking enables accurate reconstruction of displacement field, and enables effective identification mechanical heterogeneity that can be used as a biomarker for cancer diagnosis and tumor margin assessment.

Original languageEnglish (US)
Title of host publicationOptical Elastography and Tissue Biomechanics VII
EditorsKirill V. Larin, Giuliano Scarcelli
PublisherSPIE
ISBN (Electronic)9781510632479
DOIs
StatePublished - 2020
EventOptical Elastography and Tissue Biomechanics VII 2020 - San Francisco, United States
Duration: Feb 1 2020Feb 2 2020

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11242
ISSN (Print)1605-7422

Conference

ConferenceOptical Elastography and Tissue Biomechanics VII 2020
CountryUnited States
CitySan Francisco
Period2/1/202/2/20

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

Keywords

  • algorithm
  • optical coherence elastography
  • tissue characterization

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