Spatial coordinate corrected motion tracking for optical coherence elastography

Xuan Liu, Basil Hubbi, Xianlian Zhou

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

We investigate a spatial coordinate correction (SCC) method to track motion with high accuracy for optical coherence elastography (OCE). Through SCC, we refer the displacement field tracked by optical coherence tomography (OCT) in the loaded sample to individual material points defined in a fixed coordinate system. SCC allows OCE to perform spatially and temporally unambiguous tracking of displacement and enables accurate mechanical characterization of biological tissue for cancer diagnosis and tumor margin assessment. In this study, we validated the effectiveness of motion tracking based on SCC using experimental OCE data obtained from ex vivo human breast tissues.

Original languageEnglish (US)
Pages (from-to)6160-6171
Number of pages12
JournalBiomedical Optics Express
Volume10
Issue number12
DOIs
StatePublished - Dec 1 2019

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

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