(Chemical Equation Presented) An addition/elimination reaction of organolithium reagents to silylated ββf-difluorostyrene derivatives followed by a bromination/ desilicobromination reaction provides a simple and effective synthetic approach to a wide range of bromofluoroalkenes (up to >97/3). In addition, the bromofluoroalkenes can be used in Pd-catalyzed transformations giving access to both tri- and tetrasubstituted fluoroalkenes.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Feb 5 2009|
All Science Journal Classification (ASJC) codes
- Physical and Theoretical Chemistry
- Organic Chemistry