Study of the multi-binding biotinylated Iron oxide nanoparticles (biotin-IONPs) as a promising versatile label material for magnetic biodetection devices

Yimeng Du; P. W.T. Pong

doi:10.1109/ISNE.2016.7543347

Study of the multi-binding biotinylated Iron oxide nanoparticles (biotin-IONPs) as a promising versatile label material for magnetic biodetection devices

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

By realizing the multi-binding of magnetic labels with each biomolecule, the sensitivity of magnetic biodetection devices can be improved. In this study, biotinylated iron oxide nanoparticles (biotin-IONPs) were synthesized, and their multi-binding with streptavidin-functionalized biomolecules was investigated. The final biotin-IONPs with 17 nm magnetic core size exhibit superparamagnetic behavior, hydrophilic stability, and multi-binding ability with streptavidin-functionalized antibodies both on gold surfaces and suspended in solution. Consequently, biotin-IONPs are promising magnetic label materials for the improvement of magnetic biodetection devices.

Original language	English (US)
Title of host publication	2016 5th International Symposium on Next-Generation Electronics, ISNE 2016
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9781509024391
DOIs	https://doi.org/10.1109/ISNE.2016.7543347
State	Published - Aug 12 2016
Externally published	Yes
Event	5th International Symposium on Next-Generation Electronics, ISNE 2016 - Hsinchu, Taiwan, Province of China Duration: May 4 2016 → May 6 2016

Publication series

Name	2016 5th International Symposium on Next-Generation Electronics, ISNE 2016

Conference

Conference	5th International Symposium on Next-Generation Electronics, ISNE 2016
Country/Territory	Taiwan, Province of China
City	Hsinchu
Period	5/4/16 → 5/6/16

All Science Journal Classification (ASJC) codes

Electrical and Electronic Engineering
Electronic, Optical and Magnetic Materials

Keywords

Magnetic biodetection
biotin
iron oxide nanoparticles (IONPs)

Access to Document

10.1109/ISNE.2016.7543347

Cite this

Du, Y., & Pong, P. W. T. (2016). Study of the multi-binding biotinylated Iron oxide nanoparticles (biotin-IONPs) as a promising versatile label material for magnetic biodetection devices. In 2016 5th International Symposium on Next-Generation Electronics, ISNE 2016 Article 7543347 (2016 5th International Symposium on Next-Generation Electronics, ISNE 2016). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ISNE.2016.7543347

Du, Yimeng ; Pong, P. W.T. / Study of the multi-binding biotinylated Iron oxide nanoparticles (biotin-IONPs) as a promising versatile label material for magnetic biodetection devices. 2016 5th International Symposium on Next-Generation Electronics, ISNE 2016. Institute of Electrical and Electronics Engineers Inc., 2016. (2016 5th International Symposium on Next-Generation Electronics, ISNE 2016).

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title = "Study of the multi-binding biotinylated Iron oxide nanoparticles (biotin-IONPs) as a promising versatile label material for magnetic biodetection devices",

abstract = "By realizing the multi-binding of magnetic labels with each biomolecule, the sensitivity of magnetic biodetection devices can be improved. In this study, biotinylated iron oxide nanoparticles (biotin-IONPs) were synthesized, and their multi-binding with streptavidin-functionalized biomolecules was investigated. The final biotin-IONPs with 17 nm magnetic core size exhibit superparamagnetic behavior, hydrophilic stability, and multi-binding ability with streptavidin-functionalized antibodies both on gold surfaces and suspended in solution. Consequently, biotin-IONPs are promising magnetic label materials for the improvement of magnetic biodetection devices.",

keywords = "Magnetic biodetection, biotin, iron oxide nanoparticles (IONPs)",

author = "Yimeng Du and Pong, {P. W.T.}",

note = "Publisher Copyright: {\textcopyright} 2016 IEEE.; 5th International Symposium on Next-Generation Electronics, ISNE 2016 ; Conference date: 04-05-2016 Through 06-05-2016",

year = "2016",

month = aug,

day = "12",

doi = "10.1109/ISNE.2016.7543347",

language = "English (US)",

series = "2016 5th International Symposium on Next-Generation Electronics, ISNE 2016",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

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Du, Y & Pong, PWT 2016, Study of the multi-binding biotinylated Iron oxide nanoparticles (biotin-IONPs) as a promising versatile label material for magnetic biodetection devices. in 2016 5th International Symposium on Next-Generation Electronics, ISNE 2016., 7543347, 2016 5th International Symposium on Next-Generation Electronics, ISNE 2016, Institute of Electrical and Electronics Engineers Inc., 5th International Symposium on Next-Generation Electronics, ISNE 2016, Hsinchu, Taiwan, Province of China, 5/4/16. https://doi.org/10.1109/ISNE.2016.7543347

Study of the multi-binding biotinylated Iron oxide nanoparticles (biotin-IONPs) as a promising versatile label material for magnetic biodetection devices. / Du, Yimeng; Pong, P. W.T.
2016 5th International Symposium on Next-Generation Electronics, ISNE 2016. Institute of Electrical and Electronics Engineers Inc., 2016. 7543347 (2016 5th International Symposium on Next-Generation Electronics, ISNE 2016).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Study of the multi-binding biotinylated Iron oxide nanoparticles (biotin-IONPs) as a promising versatile label material for magnetic biodetection devices

AU - Du, Yimeng

AU - Pong, P. W.T.

PY - 2016/8/12

Y1 - 2016/8/12

N2 - By realizing the multi-binding of magnetic labels with each biomolecule, the sensitivity of magnetic biodetection devices can be improved. In this study, biotinylated iron oxide nanoparticles (biotin-IONPs) were synthesized, and their multi-binding with streptavidin-functionalized biomolecules was investigated. The final biotin-IONPs with 17 nm magnetic core size exhibit superparamagnetic behavior, hydrophilic stability, and multi-binding ability with streptavidin-functionalized antibodies both on gold surfaces and suspended in solution. Consequently, biotin-IONPs are promising magnetic label materials for the improvement of magnetic biodetection devices.

AB - By realizing the multi-binding of magnetic labels with each biomolecule, the sensitivity of magnetic biodetection devices can be improved. In this study, biotinylated iron oxide nanoparticles (biotin-IONPs) were synthesized, and their multi-binding with streptavidin-functionalized biomolecules was investigated. The final biotin-IONPs with 17 nm magnetic core size exhibit superparamagnetic behavior, hydrophilic stability, and multi-binding ability with streptavidin-functionalized antibodies both on gold surfaces and suspended in solution. Consequently, biotin-IONPs are promising magnetic label materials for the improvement of magnetic biodetection devices.

KW - Magnetic biodetection

KW - biotin

KW - iron oxide nanoparticles (IONPs)

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Du Y, Pong PWT. Study of the multi-binding biotinylated Iron oxide nanoparticles (biotin-IONPs) as a promising versatile label material for magnetic biodetection devices. In 2016 5th International Symposium on Next-Generation Electronics, ISNE 2016. Institute of Electrical and Electronics Engineers Inc. 2016. 7543347. (2016 5th International Symposium on Next-Generation Electronics, ISNE 2016). doi: 10.1109/ISNE.2016.7543347

Study of the multi-binding biotinylated Iron oxide nanoparticles (biotin-IONPs) as a promising versatile label material for magnetic biodetection devices

Abstract

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All Science Journal Classification (ASJC) codes

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