@inproceedings{8de06ac3ff134e739f99cb35f20fc50d,
title = "Substrate effect on dynamic indentation measurement of biological cell properties",
abstract = "Viscoelastic mechanical properties of biological cells are commonly measured using atomic force microscope (AFM) dynamic indentation method with spherical tips. Storage and loss modulii of cells are then computed from the indentation force-displacement response under dynamic loading conditions. It is shown in current numerical simulations that those modulii computed based on existing analysis can not reflect the true values due to the substrate effect. This effect can alter the indentation modulus by changing the geometric relations between the indentation displacement and the contact area. Typically, the cell modulii are significantly overestimated in the existing indentation analysis.",
author = "Guoxin Cao and Namas Chandra",
year = "2009",
doi = "10.1557/proc-1187-kk05-36",
language = "English (US)",
isbn = "9781605111605",
series = "Materials Research Society Symposium Proceedings",
publisher = "Materials Research Society",
pages = "121--126",
booktitle = "Structure-Property Relationships in Biomineralized and Biomimetic Composites",
address = "United States",
note = "2009 MRS Spring Meeting ; Conference date: 14-04-2009 Through 17-04-2009",
}