Sustained Release of Poorly Water-Soluble Drug from Hydrophilic Polymeric Film Sandwiched Between Hydrophobic Layers

Keyphrases

• Poorly Water-soluble Drugs 100%
• Sustained Release 100%
• Drug Loading 100%
• Polymeric Films 100%
• Hydrophobic Layer 100%
• Slurry 50%
• Fenofibrate 50%
• Hydroxypropyl Methylcellulose 50%
• Matrix Layers 50%
• Characterization Techniques 25%
• Proof of Concept Study 25%
• Polycaprolactone 25%
• Flow-through 25%
• Drug Content Uniformity 25%
• Two Dimensional 25%
• Polymeric Layer 25%
• Layer Thickness 25%
• Imaging Systems 25%
• In Films 25%
• Rate Limiting 25%
• Non-Fickian 25%
• Plasticizer 25%
• Fickian Diffusion 25%
• Anomalous Diffusion 25%
• Thick Film 25%
• Circular Shape 25%
• High Drug Loading 25%
• Surface Dissolution Imaging 25%
• Hydrophilic Silica 25%
• Punching 25%
• Drug Release Rate 25%
• Diffusion Film 25%
• Micronized Fenofibrate 25%
• Homogeneously Dispersed 25%
• Drug Matrix 25%
• Formulation Preparation 25%
• Precursor Preparation 25%

Engineering

• Hydrophobic 100%
• Hydrophilicity 100%
• Proof-of-Concept 33%
• Thin Films 33%
• Two Dimensional 33%
• Polymeric Layer 33%
• Layer Thickness 33%
• Imaging Systems 33%
• Fickian Diffusion 33%
• Release Rate 33%
• Middle Layer 33%
• Hydrophilic Silica 33%
• Caprolactone 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Sustained Release 100%
• Fenofibrate 100%
• Hydroxypropylmethylcellulose 66%
• Drug Release 33%
• Polycaprolactone 33%
• Plasticizer 33%
• Silicon Dioxide 33%