@article{f6760fc076064606b397e37aaad1c1b4,
title = "Sydnone-Based Approach to Heterohelicenes through 1,3-Dipolar-Cycloadditions",
abstract = "The first approach to pyrazole-containing helicenes via sydnone-aryne [3 + 2]-cycloaddition is described. An unprecedented regioselectivity in the cycloaddition step toward the more sterically constrained product was observed in the presence of extended aromatic scaffolds. DFT calculations enabled understanding the origin of this unexpected selectivity.",
author = "Exp{\'e}dite Yen-Pon and Champagne, {Pier Alexandre} and Lucie Plougastel and Sandra Gabillet and Pierre Thu{\'e}ry and Mizuki Johnson and Gilles Muller and Gr{\'e}gory Pieters and Fr{\'e}d{\'e}ric Taran and Houk, {K. N.} and Davide Audisio",
note = "Funding Information: This work was supported by CEA and ANR (ANR-17-CE07-0035-01) and the U.S. National Science Foundation (CHE-1361104). P.A.C. gratefully acknowledges the Fonds de recherche du Que{\'b} ec − Nature et Technologies for a postdoctoral fellowship. Computations were performed on the Hoffman2 cluster at UCLA. G.M. acknowledges the NIH Minority Biomedical Research Support (Grant 1 SC3 GM089589-08) and the Henry Dreyfus Teacher-Scholar Award for financial support. The authors thank C. Chollet, E. Marcon, A. Goudet, S. Lebrequier, and D.-A. Buisson (DRF-JOLIOT-SCBM, CEA) for excellent analytical support. We wish to acknowledge Dr. P. Dauban (ICSN, CNRS, France) for helpful discussions. Publisher Copyright: {\textcopyright} 2019 American Chemical Society. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.",
year = "2019",
month = jan,
day = "30",
doi = "10.1021/jacs.8b11465",
language = "English (US)",
volume = "141",
pages = "1435--1440",
journal = "Journal of the American Chemical Society",
issn = "0002-7863",
publisher = "American Chemical Society",
number = "4",
}