TY - GEN
T1 - Synthesis of corn-derived carbohydrate derivatives as effective multifunctional sunscreens
AU - Feng, Xianhong
AU - Jaffe, Michael
AU - Hammond, Willis B.
AU - East, Anthony J.
PY - 2009
Y1 - 2009
N2 - A range of novel biomass-derived sunscreens and additives were synthesized by substituting corn-produced isosorbide with different functional moieties, such as naturally-occurring cinnamic acids. Based on the different reactivity of the two isosorbide hydroxyl groups, an effective synthetic route was developed for making multifunctional molecules such as UV -absorbing polymer plasticizers and antioxidants. Isosorbide-derived UVB/UV A sunscreens and other additives were characterized by NMR, FTIR and UV spectra. A UV photostability test showed that such sunscreens not only have a high molar extinction coefficient but also a high photostability, the combination covering both UVB and UVA regions. By following this scheme, other medically-useful bio-molecules can be synthesized in the future, such as a full spectrum UV absorber and a UV -absorbing antioxidant, to name a few.
AB - A range of novel biomass-derived sunscreens and additives were synthesized by substituting corn-produced isosorbide with different functional moieties, such as naturally-occurring cinnamic acids. Based on the different reactivity of the two isosorbide hydroxyl groups, an effective synthetic route was developed for making multifunctional molecules such as UV -absorbing polymer plasticizers and antioxidants. Isosorbide-derived UVB/UV A sunscreens and other additives were characterized by NMR, FTIR and UV spectra. A UV photostability test showed that such sunscreens not only have a high molar extinction coefficient but also a high photostability, the combination covering both UVB and UVA regions. By following this scheme, other medically-useful bio-molecules can be synthesized in the future, such as a full spectrum UV absorber and a UV -absorbing antioxidant, to name a few.
UR - http://www.scopus.com/inward/record.url?scp=70349091093&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70349091093&partnerID=8YFLogxK
U2 - 10.1109/NEBC.2009.4967798
DO - 10.1109/NEBC.2009.4967798
M3 - Conference contribution
AN - SCOPUS:70349091093
SN - 9781424443628
T3 - Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
BT - NEBEC 2009 - Proceedings of the IEEE 35th Annual Northeast Bioengineering Conference
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - IEEE 35th Annual Northeast Bioengineering Conference, NEBEC 2009
Y2 - 3 April 2009 through 5 April 2009
ER -