Synthesis of corn-derived carbohydrate derivatives as effective multifunctional sunscreens

Xianhong Feng, Michael Jaffe, Willis B. Hammond, Anthony J. East

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    2 Scopus citations

    Abstract

    A range of novel biomass-derived sunscreens and additives were synthesized by substituting corn-produced isosorbide with different functional moieties, such as naturally-occurring cinnamic acids. Based on the different reactivity of the two isosorbide hydroxyl groups, an effective synthetic route was developed for making multifunctional molecules such as UV -absorbing polymer plasticizers and antioxidants. Isosorbide-derived UVB/UV A sunscreens and other additives were characterized by NMR, FTIR and UV spectra. A UV photostability test showed that such sunscreens not only have a high molar extinction coefficient but also a high photostability, the combination covering both UVB and UVA regions. By following this scheme, other medically-useful bio-molecules can be synthesized in the future, such as a full spectrum UV absorber and a UV -absorbing antioxidant, to name a few.

    Original languageEnglish (US)
    Title of host publicationNEBEC 2009 - Proceedings of the IEEE 35th Annual Northeast Bioengineering Conference
    PublisherInstitute of Electrical and Electronics Engineers Inc.
    ISBN (Print)9781424443628
    DOIs
    StatePublished - 2009
    EventIEEE 35th Annual Northeast Bioengineering Conference, NEBEC 2009 - Boston, MA, United States
    Duration: Apr 3 2009Apr 5 2009

    Publication series

    NameProceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
    ISSN (Print)1071-121X

    Other

    OtherIEEE 35th Annual Northeast Bioengineering Conference, NEBEC 2009
    Country/TerritoryUnited States
    CityBoston, MA
    Period4/3/094/5/09

    All Science Journal Classification (ASJC) codes

    • Bioengineering

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