Targeted resequencing identifies defective variants of decoy receptor 3 in pediatric-onset inflammatory bowel disease

Keyphrases

• Inflammatory Bowel Disease 100%
• TNFRSF6B 100%
• Decoy Receptor 3 (DcR3) 100%
• Targeted Resequencing 100%
• Defective Variants 100%
• Pediatric Onset 100%
• Odds Ratio 66%
• Pediatric IBD 66%
• Intervention Targets 33%
• Healthy Controls 33%
• Genome-wide Association Study 33%
• Exon 33%
• Functional Assay 33%
• Missense mutation 33%
• TNF Receptor 1 (TNFR1) 33%
• Secreted Proteins 33%
• Tumor Necrosis Factor Superfamily 33%
• Common Variation 33%
• Cultured Cells 33%
• Missense Variants 33%
• Inflammatory Cytokines 33%
• Functional Significance 33%
• Pediatric Crohn's 33%
• Protein Decoy 33%
• Crohn's 33%
• Family Members 33%
• Tumor Necrosis Factor Family 33%

Biochemistry, Genetics and Molecular Biology

• Eicosanoid Receptor 100%
• TNFRSF6B 100%
• Cell Culture 33%
• Secretion (Process) 33%
• Genome-Wide Association Study 33%
• Exon 33%
• Missense Mutation 33%
• Missense 33%
• Tumor Necrosis Factor Family 33%
• Tumor Necrosis Factor 33%
• Proinflammatory Cytokine 33%
• Tumor Necrosis Factor Receptor 33%

Neuroscience

• Inflammatory Bowel Disease 100%
• Decoy Receptor 3 100%
• Necrosis 28%
• Cell Culture 14%
• Genome-Wide Association Study 14%
• Exon 14%
• Missense Mutation 14%
• Proinflammatory Cytokine 14%
• Tumor Necrosis Factor Receptor 14%