Targets for Alzheimer's disease: Lessons learnt from flies

M. Konsolaki; D. Cohen

doi:10.1016/S1741-8372(04)02395-3

Targets for Alzheimer's disease: Lessons learnt from flies

M. Konsolaki, D. Cohen

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Abstract

Neurodegenerative diseases, including Alzheimer's disease (AD), are a major focus of the pharmaceutical industry. Recently, human genetic analyses have aided in the successful identification of a handful of genes responsible for genetically inherited forms of AD, but our understanding of basic mechanisms that lead to the more common sporadic forms of this disease is still limited.

Original language	English (US)
Pages (from-to)	64-70
Number of pages	7
Journal	Drug Discovery Today: TARGETS
Volume	3
Issue number	2
DOIs	https://doi.org/10.1016/S1741-8372(04)02395-3
State	Published - Apr 2004
Externally published	Yes

All Science Journal Classification (ASJC) codes

Drug Discovery

Keywords

Alzheimer's Disease
Drosophila
Drug Discovery
Genetics
Molecular Medicine
Neurobiology
Pharmaceutical Science
beta-amyloid
disease pathways
genetic analysis

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10.1016/S1741-8372(04)02395-3

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abstract = "Neurodegenerative diseases, including Alzheimer's disease (AD), are a major focus of the pharmaceutical industry. Recently, human genetic analyses have aided in the successful identification of a handful of genes responsible for genetically inherited forms of AD, but our understanding of basic mechanisms that lead to the more common sporadic forms of this disease is still limited.",

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AB - Neurodegenerative diseases, including Alzheimer's disease (AD), are a major focus of the pharmaceutical industry. Recently, human genetic analyses have aided in the successful identification of a handful of genes responsible for genetically inherited forms of AD, but our understanding of basic mechanisms that lead to the more common sporadic forms of this disease is still limited.

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KW - Drosophila

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KW - Molecular Medicine

KW - Neurobiology

KW - Pharmaceutical Science

KW - beta-amyloid

KW - disease pathways

KW - genetic analysis

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Targets for Alzheimer's disease: Lessons learnt from flies

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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