The chorion genes of the medfly, ceratitis capitata, I: Structural and regulatory conservation of the s36 gene relative to two Drosophila species

Mary Konsolaki, Katia Komitopoulou, Peter P. Tolias, Dennis L. King, Candace Swimmer, Fotis C. Kafatos

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

We have used low stringency screening with the Drosophila meianogaster s36 chorion gene to recover its homologue from genomic and cDNA libraries of the medfly, Ceratitis capitata. The same gene has also been recovered from a genomic library of D. virills. The medfly s36 gene shows similar developmental specificity as in Drosophila (early choriogenesis). It is also specifically amplified in ovarian follicles; this is the first report of chorlon gene ampliflcatlon outside the genus Drosophila. Alignments of s36 sequences from three species show that, in addition to its regulatory conservation, the 936 gene is extensively conserved in sequence, in a region corresponding to a central protein domain, and in short regions of 5′ flanking DNA that might correspond to cis-regulatory elements.

Original languageEnglish (US)
Pages (from-to)1731-1737
Number of pages7
JournalNucleic Acids Research
Volume18
Issue number7
DOIs
StatePublished - Apr 11 1990
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Genetics

Fingerprint Dive into the research topics of 'The chorion genes of the medfly, ceratitis capitata, I: Structural and regulatory conservation of the s36 gene relative to two Drosophila species'. Together they form a unique fingerprint.

Cite this