TY - JOUR
T1 - The complexity of spontaneous brain activity changes in schizophrenia, bipolar disorder, and ADHD was examined using different variations of entropy
AU - Guan, Sihai
AU - Wan, Dongyu
AU - Zhao, Rong
AU - Canario, Edgar
AU - Meng, Chun
AU - Biswal, Bharat B.
N1 - Funding Information:
This work was supported by the National Natural Science Foundation of China (61871420), the Central Universities Foundation, Southwest Minzu University (2021XJTD01), the introduction of talent, Southwest MinZu University, funding research projects start (RQD2021064), and the Natural Science Foundation of Henan Polytechnic University (B2021‐38).
Publisher Copyright:
© 2022 The Authors. Human Brain Mapping published by Wiley Periodicals LLC.
PY - 2023/1
Y1 - 2023/1
N2 - Adult attention deficit/hyperactivity disorder (ADHD), schizophrenia (SCHZ), and bipolar disorder (BP) have common symptoms and differences, and the underlying neural mechanisms are still unclear. This article will thoroughly discuss the differences between ADHD, BP, and SCHZ (31 healthy control and 31 ADHD; 34 healthy control and 34 BP; 42 healthy control and 42 SCHZ) relative to healthy subjects in combination with three atlases (et al., the Brainnetome atlas, the Dosenbach atlas, the Power atlas) and seven entropies (et al., approximate entropy (ApEn), sample entropy (SaEn), permutation entropy (PeEn), fuzzy entropy (FuEn), differential entropy (DiffEn), range entropy (RaEn), and dispersion entropy (DispEn)), as well as the prominent significant brain regions, in the hope of giving information that is more suitable for analyzing different diseases' entropy. First, the reliability (et al., intraclass correlation coefficient [ICC]) of seven kinds of entropy is calculated and analyzed by using the MSC dataset (10 subjects and 100 sessions in total) and simulation data; then, seven types of entropy and multiscale entropy expanded based on seven kinds of entropy are used to explore the differences and brain regions of ADHD, BP, and SCHZ relative to healthy subjects; and finally, by verifying the classification performance of the seven information entropies on ADHD, BP, and SCHZ, the effectiveness of the seven entropy methods is evaluated through these three methods. The core brain regions that affect the classification are given, and DiffEn performed best on ADHD, SaEn for BP, and RaEn for SCHZ.
AB - Adult attention deficit/hyperactivity disorder (ADHD), schizophrenia (SCHZ), and bipolar disorder (BP) have common symptoms and differences, and the underlying neural mechanisms are still unclear. This article will thoroughly discuss the differences between ADHD, BP, and SCHZ (31 healthy control and 31 ADHD; 34 healthy control and 34 BP; 42 healthy control and 42 SCHZ) relative to healthy subjects in combination with three atlases (et al., the Brainnetome atlas, the Dosenbach atlas, the Power atlas) and seven entropies (et al., approximate entropy (ApEn), sample entropy (SaEn), permutation entropy (PeEn), fuzzy entropy (FuEn), differential entropy (DiffEn), range entropy (RaEn), and dispersion entropy (DispEn)), as well as the prominent significant brain regions, in the hope of giving information that is more suitable for analyzing different diseases' entropy. First, the reliability (et al., intraclass correlation coefficient [ICC]) of seven kinds of entropy is calculated and analyzed by using the MSC dataset (10 subjects and 100 sessions in total) and simulation data; then, seven types of entropy and multiscale entropy expanded based on seven kinds of entropy are used to explore the differences and brain regions of ADHD, BP, and SCHZ relative to healthy subjects; and finally, by verifying the classification performance of the seven information entropies on ADHD, BP, and SCHZ, the effectiveness of the seven entropy methods is evaluated through these three methods. The core brain regions that affect the classification are given, and DiffEn performed best on ADHD, SaEn for BP, and RaEn for SCHZ.
KW - (multiscale)entropies
KW - ADHD/BP/SCHZ
KW - different atlases
KW - resting-state fMRI
KW - test–retest reliability
UR - http://www.scopus.com/inward/record.url?scp=85141998152&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85141998152&partnerID=8YFLogxK
U2 - 10.1002/hbm.26129
DO - 10.1002/hbm.26129
M3 - Article
C2 - 36358029
AN - SCOPUS:85141998152
SN - 1065-9471
VL - 44
SP - 94
EP - 118
JO - Human Brain Mapping
JF - Human Brain Mapping
IS - 1
ER -