The role of electrical coupling in generating and modulating oscillations in a neuronal network

Christina Mouser; Amitabha Bose; Farzan Nadim

doi:10.1016/j.mbs.2016.05.001

The role of electrical coupling in generating and modulating oscillations in a neuronal network

Christina Mouser, Amitabha Bose, Farzan Nadim

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

A simplified model of the crustacean gastric mill network is considered. Rhythmic activity in this network has largely been attributed to half center oscillations driven by mutual inhibition. We use mathematical modeling and dynamical systems theory to show that rhythmic oscillations in this network may also depend on, or even arise from, a voltage-dependent electrical coupling between one of the cells in the half-center network and a projection neuron that lies outside of the network. This finding uncovers a potentially new mechanism for the generation of oscillations in neuronal networks.

Original language	English (US)
Pages (from-to)	11-21
Number of pages	11
Journal	Mathematical Biosciences
Volume	278
DOIs	https://doi.org/10.1016/j.mbs.2016.05.001
State	Published - Aug 1 2016

All Science Journal Classification (ASJC) codes

Statistics and Probability
Modeling and Simulation
General Biochemistry, Genetics and Molecular Biology
General Immunology and Microbiology
General Agricultural and Biological Sciences
Applied Mathematics

Keywords

Electrical coupling
Half-center oscillator
Phase-plane analysis

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10.1016/j.mbs.2016.05.001

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title = "The role of electrical coupling in generating and modulating oscillations in a neuronal network",

abstract = "A simplified model of the crustacean gastric mill network is considered. Rhythmic activity in this network has largely been attributed to half center oscillations driven by mutual inhibition. We use mathematical modeling and dynamical systems theory to show that rhythmic oscillations in this network may also depend on, or even arise from, a voltage-dependent electrical coupling between one of the cells in the half-center network and a projection neuron that lies outside of the network. This finding uncovers a potentially new mechanism for the generation of oscillations in neuronal networks.",

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T1 - The role of electrical coupling in generating and modulating oscillations in a neuronal network

AU - Mouser, Christina

AU - Bose, Amitabha

AU - Nadim, Farzan

PY - 2016/8/1

Y1 - 2016/8/1

N2 - A simplified model of the crustacean gastric mill network is considered. Rhythmic activity in this network has largely been attributed to half center oscillations driven by mutual inhibition. We use mathematical modeling and dynamical systems theory to show that rhythmic oscillations in this network may also depend on, or even arise from, a voltage-dependent electrical coupling between one of the cells in the half-center network and a projection neuron that lies outside of the network. This finding uncovers a potentially new mechanism for the generation of oscillations in neuronal networks.

AB - A simplified model of the crustacean gastric mill network is considered. Rhythmic activity in this network has largely been attributed to half center oscillations driven by mutual inhibition. We use mathematical modeling and dynamical systems theory to show that rhythmic oscillations in this network may also depend on, or even arise from, a voltage-dependent electrical coupling between one of the cells in the half-center network and a projection neuron that lies outside of the network. This finding uncovers a potentially new mechanism for the generation of oscillations in neuronal networks.

KW - Electrical coupling

KW - Half-center oscillator

KW - Phase-plane analysis

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SN - 0025-5564

VL - 278

SP - 11

EP - 21

JO - Mathematical Biosciences

JF - Mathematical Biosciences

ER -

The role of electrical coupling in generating and modulating oscillations in a neuronal network

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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