TY - JOUR
T1 - Theoretical analysis of non-steady-state, pulse introduction membrane extraction with a sorbent trap interface for gas chromatographic detection
AU - Guo, Xuemei
AU - Mitra, Somenath
PY - 1999/10/15
Y1 - 1999/10/15
N2 - Polymeric membranes have been used for extraction of organic compounds from an aqueous matrix, where the analysis is carried out on-line using a GC, a HPLC, or a mass spectrometer. High extraction selectivity and permeation rate can be achieved by choosing an appropriate membrane and optimum operating conditions. The sample can be introduced either continuously or as a pulse into the membrane. The former approach is based on steady-state permeation, while the latter is not. In this paper, pulse introduction membrane extraction is presented for on-line gas chromatography using a sorbent trap as an interface. A mathematical model that incorporates boundary layer effects has been developed, and the process parameters that affect sensitivity and lag time have been studied. It is observed that there is a trade-off between sensitivity and lag time; larger sample volume and lower flow rate enhance sensitivity but also increase lag time.
AB - Polymeric membranes have been used for extraction of organic compounds from an aqueous matrix, where the analysis is carried out on-line using a GC, a HPLC, or a mass spectrometer. High extraction selectivity and permeation rate can be achieved by choosing an appropriate membrane and optimum operating conditions. The sample can be introduced either continuously or as a pulse into the membrane. The former approach is based on steady-state permeation, while the latter is not. In this paper, pulse introduction membrane extraction is presented for on-line gas chromatography using a sorbent trap as an interface. A mathematical model that incorporates boundary layer effects has been developed, and the process parameters that affect sensitivity and lag time have been studied. It is observed that there is a trade-off between sensitivity and lag time; larger sample volume and lower flow rate enhance sensitivity but also increase lag time.
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U2 - 10.1021/ac981226b
DO - 10.1021/ac981226b
M3 - Article
AN - SCOPUS:0032706332
SN - 0003-2700
VL - 71
SP - 4587
EP - 4593
JO - Analytical Chemistry
JF - Analytical Chemistry
IS - 20
ER -